General Structure Information 1ua2 CDK7 crystal structure of human cdk7 3.02Å AUTH G.LOLLI,E.D.LOWE,N.R.BROWN,L.N.JOHNSONTITL THE CRYSTAL STRUCTURE OF HUMAN CDK7 AND ITS PROTEINTITL 2 RECOGNITION PROPERTIESREF STRUCTURE V. 12 2067 2004REFN ISSN 0969-2126PMID 15530371DOI 10.1016/J.STR.2004.08.013 Variant Set Distributions Mapped Variants
General Structure Information 2rop ATP7B solution structure of domains 3 and 4 of human atp7b -1.0Å AUTH L.BANCI,I.BERTINI,F.CANTINI,A.C.ROSENZWEIG,AUTH 2 L.A.YATSUNYKTITL METAL BINDING DOMAINS 3 AND 4 OF THE WILSONTITL 2 DISEASE PROTEIN: SOLUTION STRUCTURE ANDTITL 3 INTERACTION WITH THE COPPER(I) CHAPERONE HAH1REF BIOCHEMISTRY V. 47 7423 2008REFN ISSN 0006-2960PMID 18558714DOI 10.1021/BI8004736 Variant Set Distributions Mapped […]
General Structure Information 1s9i MAP2K2 x-ray structure of the human mitogen-activated protein kinase kinase 2 (mek2)in a complex with ligand and mgatp 3.2Å AUTH J.F.OHREN,H.CHEN,A.PAVLOVSKY,C.WHITEHEAD,E.ZHANG,AUTH 2 P.KUFFA,C.YAN,P.MCCONNELL,C.SPESSARD,C.BANOTAI,AUTH 3 W.T.MUELLER,A.DELANEY,C.OMER,J.SEBOLT-LEOPOLD,AUTH 4 D.T.DUDLEY,I.K.LEUNG,C.FLAMME,J.WARMUS,M.KAUFMAN,AUTH 5 S.BARRETT,H.TECLE,C.A.HASEMANNTITL STRUCTURES OF HUMAN MAP KINASE KINASE 1 (MEK1) ANDTITL 2 MEK2 DESCRIBE NOVEL NONCOMPETITIVE KINASETITL 3 INHIBITION.REF NAT.STRUCT.MOL.BIOL. V. 11 1192 2004REFN […]
General Structure Information 2z3r IL15 crystal structure of the il-15/il-15ra complex 2.0Å AUTH M.CHIRIFU,C.HAYASHI,T.NAKAMURA,S.TOMA,T.SHUTO,H.KAI,AUTH 2 Y.YAMAGATA,S.J.DAVIS,S.IKEMIZUTITL CRYSTAL STRUCTURE OF THE IL-15-IL-15RALPHA COMPLEX, ATITL 2 CYTOKINE-RECEPTOR UNIT PRESENTED IN TRANSREF NAT.IMMUNOL. V. 8 1001 2007REFN ISSN 1529-2908PMID 17643103DOI 10.1038/NI1492 Variant Set Distributions Mapped Variants
General Structure Information 2gwf USP8 structure of a usp8-nrdp1 complex 2.3Å AUTH G.V.AVVAKUMOV,J.R.WALKER,S.XUE,P.J.FINERTY JR.,F.MACKENZIE,AUTH 2 E.M.NEWMAN,S.DHE-PAGANONTITL AMINO-TERMINAL DIMERIZATION, NRDP1-RHODANESE INTERACTION,TITL 2 AND INHIBITED CATALYTIC DOMAIN CONFORMATION OF THETITL 3 UBIQUITIN-SPECIFIC PROTEASE 8 (USP8).REF J.BIOL.CHEM. V. 281 38061 2006REFN ISSN 0021-9258PMID 17035239DOI 10.1074/JBC.M606704200 Variant Set Distributions Mapped Variants
General Structure Information 3aad TAF1 structure of the histone chaperone cia/asf1-double bromodomain complex linking histone modifications and site-specific histone eviction 3.3Å AUTH Y.AKAI,N.ADACHI,Y.HAYASHI,M.EITOKU,N.SANO,R.NATSUME,N.KUDO,AUTH 2 M.TANOKURA,T.SENDA,M.HORIKOSHITITL STRUCTURE OF THE HISTONE CHAPERONE CIA/ASF1-DOUBLETITL 2 BROMODOMAIN COMPLEX LINKING HISTONE MODIFICATIONS ANDTITL 3 SITE-SPECIFIC HISTONE EVICTIONREF PROC.NATL.ACAD.SCI.USA V. 107 8153 2010REFN ISSN 0027-8424PMID 20393127DOI 10.1073/PNAS.0912509107 Variant Set Distributions Ripley’s […]
General Structure Information 3nmz APC crytal structure of apc complexed with asef 3.01Å AUTH Z.ZHANG,L.CHEN,L.GAO,K.LIN,G.WUTITL CRYSTAL STRUCTURE OF APC COMPLEXED WITH ASEFREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants