General Structure Information 3oe8 CXCR4 crystal structure of the cxcr4 chemokine receptor in complex with a small molecule antagonist it1t in p1 spacegroup 3.1Å AUTH B.WU,E.Y.CHIEN,C.D.MOL,G.FENALTI,W.LIU,V.KATRITCH,R.ABAGYAN,AUTH 2 A.BROOUN,P.WELLS,F.C.BI,D.J.HAMEL,P.KUHN,T.M.HANDEL,AUTH 3 V.CHEREZOV,R.C.STEVENSTITL STRUCTURES OF THE CXCR4 CHEMOKINE GPCR WITH SMALL-MOLECULETITL 2 AND CYCLIC PEPTIDE ANTAGONISTS.REF SCIENCE V. 330 1066 2010REFN ISSN 0036-8075PMID 20929726DOI 10.1126/SCIENCE.1194396 Variant Set Distributions […]
General Structure Information 3oe8 CXCR4 crystal structure of the cxcr4 chemokine receptor in complex with a small molecule antagonist it1t in p1 spacegroup 3.1Å AUTH B.WU,E.Y.CHIEN,C.D.MOL,G.FENALTI,W.LIU,V.KATRITCH,R.ABAGYAN,AUTH 2 A.BROOUN,P.WELLS,F.C.BI,D.J.HAMEL,P.KUHN,T.M.HANDEL,AUTH 3 V.CHEREZOV,R.C.STEVENSTITL STRUCTURES OF THE CXCR4 CHEMOKINE GPCR WITH SMALL-MOLECULETITL 2 AND CYCLIC PEPTIDE ANTAGONISTS.REF SCIENCE V. 330 1066 2010REFN ISSN 0036-8075PMID 20929726DOI 10.1126/SCIENCE.1194396 Variant Set Distributions […]
General Structure Information 4mbs CCR5 crystal structure of the ccr5 chemokine receptor 2.71Å AUTH Q.TAN,Y.ZHU,J.LI,Z.CHEN,G.W.HAN,I.KUFAREVA,T.LI,L.MA,AUTH 2 G.FENALTI,J.LI,W.ZHANG,X.XIE,H.YANG,H.JIANG,V.CHEREZOV,AUTH 3 H.LIU,R.C.STEVENS,Q.ZHAO,B.WUTITL STRUCTURE OF THE CCR5 CHEMOKINE RECEPTOR-HIV ENTRY INHIBITORTITL 2 MARAVIROC COMPLEX.REF SCIENCE V. 341 1387 2013REFN ISSN 0036-8075PMID 24030490DOI 10.1126/SCIENCE.1241475 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3c59 GLP1R crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain 2.3Å AUTH S.RUNGE,H.THOGERSEN,K.MADSEN,J.LAU,R.RUDOLPHTITL CRYSTAL STRUCTURE OF THE LIGAND-BOUND GLUCAGON-LIKETITL 2 PEPTIDE-1 RECEPTOR EXTRACELLULAR DOMAINREF J.BIOL.CHEM. V. 283 11340 2008REFN ISSN 0021-9258PMID 18287102DOI 10.1074/JBC.M708740200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3pbl DRD3 structure of the human dopamine d3 receptor in complex with eticlopride 2.89Å AUTH E.Y.CHIEN,W.LIU,Q.ZHAO,V.KATRITCH,G.W.HAN,M.A.HANSON,L.SHI,AUTH 2 A.H.NEWMAN,J.A.JAVITCH,V.CHEREZOV,R.C.STEVENSTITL STRUCTURE OF THE HUMAN DOPAMINE D3 RECEPTOR IN COMPLEX WITHTITL 2 A D2/D3 SELECTIVE ANTAGONIST.REF SCIENCE V. 330 1091 2010REFN ISSN 0036-8075PMID 21097933DOI 10.1126/SCIENCE.1197410 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3nyo GRK6 crystal structure of g protein-coupled receptor kinase 6 in complex with amp 2.92Å AUTH C.A.BOGUTH,P.SINGH,C.C.HUANG,J.J.TESMERTITL MOLECULAR BASIS FOR ACTIVATION OF G PROTEIN-COUPLED RECEPTORTITL 2 KINASES.REF EMBO J. V. 29 3249 2010REFN ISSN 0261-4189PMID 20729810DOI 10.1038/EMBOJ.2010.206 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants