Assessment of Structural Intolerance and Durability
General Structure Information 2v0o FCHO2 fcho2 f-bar domain 2.3Å AUTH W.M.HENNE,H.M.KENT,M.J.G.FORD,B.G.HEDGE,O.DAUMKE,AUTH 2 P.J.BUTLER,R.MITTAL,R.LANGEN,P.R.EVANS,H.T.MCMAHONTITL STRUCTURE AND ANALYSIS OF FCHO2 F-BAR DOMAIN: ATITL 2 DIMERIZING AND MEMBRANE RECRUITMENT MODULE THATTITL 3 EFFECTS MEMBRANE CURVATURE.REF STRUCTURE V. 15 839 2007REFN ISSN 0969-2126PMID 17540576DOI 10.1016/J.STR.2007.05.002 Variant Set Distributions Mapped Variants
General Structure Information 3l5k HDHD1 the crystal structure of human haloacid dehalogenase-like hydrolase domain containing 1a (hdhd1a) 2.0Å AUTH E.UGOCHUKWU,K.GUO,S.PICAUD,J.MUNIZ,C.ALLERSTON,AUTH 2 F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,AUTH 3 A.EDWARDS,W.W.YUE,K.L.KAVANAGH,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE CRYSTAL STRUCTURE OF HUMAN HALOACIDTITL 2 DEHALOGENASE-LIKE HYDROLASE DOMAIN CONTAINING 1ATITL 3 (HDHD1A)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3l5k HDHD1 the crystal structure of human haloacid dehalogenase-like hydrolase domain containing 1a (hdhd1a) 2.0Å AUTH E.UGOCHUKWU,K.GUO,S.PICAUD,J.MUNIZ,C.ALLERSTON,AUTH 2 F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,AUTH 3 A.EDWARDS,W.W.YUE,K.L.KAVANAGH,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE CRYSTAL STRUCTURE OF HUMAN HALOACIDTITL 2 DEHALOGENASE-LIKE HYDROLASE DOMAIN CONTAINING 1ATITL 3 (HDHD1A)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3l5k HDHD1 the crystal structure of human haloacid dehalogenase-like hydrolase domain containing 1a (hdhd1a) 2.0Å AUTH E.UGOCHUKWU,K.GUO,S.PICAUD,J.MUNIZ,C.ALLERSTON,AUTH 2 F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,AUTH 3 A.EDWARDS,W.W.YUE,K.L.KAVANAGH,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE CRYSTAL STRUCTURE OF HUMAN HALOACIDTITL 2 DEHALOGENASE-LIKE HYDROLASE DOMAIN CONTAINING 1ATITL 3 (HDHD1A)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2jed PRKCQ the crystal structure of the kinase domain of the protein kinase c theta in complex with nvp-xaa228 at 2.32a resolution. 2.32Å AUTH W.STARK,F.BITSCH,A.BERNER,F.BUELENS,P.GRAFF,AUTH 2 H.DEPERSIN,G.FENDRICH,M.GEISER,R.KNECHT,J.RAHUEL,AUTH 3 G.RUMMEL,J.M.SCHLAEPPI,R.SCHMITZ,A.STRAUSS,J.WAGNERTITL THE CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF THETITL 2 PROTEIN KINASE C THETA IN COMPLEX WITH NVP-XAA228REF TO BE PUBLISHEDREFN Variant Set […]
General Structure Information 2w5z KMT2A ternary complex of the mixed lineage leukaemia (mll1) set domain with the cofactor product s-adenosylhomocysteine and histone peptide. 2.2Å AUTH S.M.SOUTHALL,P.S.WONG,Z.ODHO,S.M.ROE,J.R.WILSONTITL STRUCTURAL BASIS FOR THE REQUIREMENT OF ADDITIONALTITL 2 FACTORS FOR MLL1 SET DOMAIN ACTIVITY ANDTITL 3 RECOGNITION OF EPIGENETIC MARKS.REF MOL.CELL V. 33 181 2009REFN ISSN 1097-2765PMID 19187761DOI 10.1016/J.MOLCEL.2008.12.029 […]
General Structure Information 2w5z KMT2A ternary complex of the mixed lineage leukaemia (mll1) set domain with the cofactor product s-adenosylhomocysteine and histone peptide. 2.2Å AUTH S.M.SOUTHALL,P.S.WONG,Z.ODHO,S.M.ROE,J.R.WILSONTITL STRUCTURAL BASIS FOR THE REQUIREMENT OF ADDITIONALTITL 2 FACTORS FOR MLL1 SET DOMAIN ACTIVITY ANDTITL 3 RECOGNITION OF EPIGENETIC MARKS.REF MOL.CELL V. 33 181 2009REFN ISSN 1097-2765PMID 19187761DOI 10.1016/J.MOLCEL.2008.12.029 […]
General Structure Information 2w5z KMT2A ternary complex of the mixed lineage leukaemia (mll1) set domain with the cofactor product s-adenosylhomocysteine and histone peptide. 2.2Å AUTH S.M.SOUTHALL,P.S.WONG,Z.ODHO,S.M.ROE,J.R.WILSONTITL STRUCTURAL BASIS FOR THE REQUIREMENT OF ADDITIONALTITL 2 FACTORS FOR MLL1 SET DOMAIN ACTIVITY ANDTITL 3 RECOGNITION OF EPIGENETIC MARKS.REF MOL.CELL V. 33 181 2009REFN ISSN 1097-2765PMID 19187761DOI 10.1016/J.MOLCEL.2008.12.029 […]
General Structure Information 2w5z KMT2A ternary complex of the mixed lineage leukaemia (mll1) set domain with the cofactor product s-adenosylhomocysteine and histone peptide. 2.2Å AUTH S.M.SOUTHALL,P.S.WONG,Z.ODHO,S.M.ROE,J.R.WILSONTITL STRUCTURAL BASIS FOR THE REQUIREMENT OF ADDITIONALTITL 2 FACTORS FOR MLL1 SET DOMAIN ACTIVITY ANDTITL 3 RECOGNITION OF EPIGENETIC MARKS.REF MOL.CELL V. 33 181 2009REFN ISSN 1097-2765PMID 19187761DOI 10.1016/J.MOLCEL.2008.12.029 […]
General Structure Information 2w5z KMT2A ternary complex of the mixed lineage leukaemia (mll1) set domain with the cofactor product s-adenosylhomocysteine and histone peptide. 2.2Å AUTH S.M.SOUTHALL,P.S.WONG,Z.ODHO,S.M.ROE,J.R.WILSONTITL STRUCTURAL BASIS FOR THE REQUIREMENT OF ADDITIONALTITL 2 FACTORS FOR MLL1 SET DOMAIN ACTIVITY ANDTITL 3 RECOGNITION OF EPIGENETIC MARKS.REF MOL.CELL V. 33 181 2009REFN ISSN 1097-2765PMID 19187761DOI 10.1016/J.MOLCEL.2008.12.029 […]