Assessment of Structural Intolerance and Durability
General Structure Information 3pq1 MTPAP crystal structure of human mitochondrial poly(a) polymerase (papd1) 3.1Å AUTH Y.BAI,S.K.SRIVASTAVA,J.H.CHANG,J.L.MANLEY,L.TONGTITL STRUCTURAL BASIS FOR DIMERIZATION AND ACTIVITY OF HUMANTITL 2 PAPD1, A NONCANONICAL POLY(A) POLYMERASE.REF MOL.CELL V. 41 311 2011REFN ISSN 1097-2765PMID 21292163DOI 10.1016/J.MOLCEL.2011.01.013 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4lt6 PAPOLG crystal structure of human poly(a) polymerase gamma 2.79Å AUTH Q.YANG,L.W.NAUSCH,G.MARTIN,W.KELLER,S.DOUBLIETITL CRYSTAL STRUCTURE OF HUMAN POLY(A) POLYMERASE GAMMA REVEALSTITL 2 A CONSERVED CATALYTIC CORE FOR CANONICAL POLY(A)TITL 3 POLYMERASES.REF J.MOL.BIOL. V. 426 43 2014REFN ISSN 0022-2836PMID 24076191DOI 10.1016/J.JMB.2013.09.025 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2d5r TOB1 crystal structure of a tob-hcaf1 complex 2.5Å AUTH M.HORIUCHI,K.TAKEUCHI,N.NODA,N.MUROYA,T.SUZUKI,AUTH 2 T.NAKAMURA,J.KAWAMURA-TSUZUKU,K.TAKAHASI,AUTH 3 T.YAMAMOTO,F.INAGAKITITL STRUCTURAL BASIS FOR THE ANTIPROLIFERATIVE ACTIVITYTITL 2 OF THE TOB-HCAF1 COMPLEX.REF J.BIOL.CHEM. V. 284 13244 2009REFN ISSN 0021-9258PMID 19276069DOI 10.1074/JBC.M809250200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants