General Structure Information
| PDB ID | 2d5r |
| HGNC Gene Label(s) | TOB1 |
| Structure Name | crystal structure of a tob-hcaf1 complex |
| Resolution | 2.5Å |
| Reference | AUTH M.HORIUCHI,K.TAKEUCHI,N.NODA,N.MUROYA,T.SUZUKI,AUTH 2 T.NAKAMURA,J.KAWAMURA-TSUZUKU,K.TAKAHASI,AUTH 3 T.YAMAMOTO,F.INAGAKITITL STRUCTURAL BASIS FOR THE ANTIPROLIFERATIVE ACTIVITYTITL 2 OF THE TOB-HCAF1 COMPLEX.REF J.BIOL.CHEM. V. 284 13244 2009REFN ISSN 0021-9258PMID 19276069DOI 10.1074/JBC.M809250200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 115 |
| Number Of SNVs | 16 |
| Number Of Permutations | 4278 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.042 |
| p-value | 0.239 |
COSMIC
| Number Of Residues | 115 |
| Number Of SNVs | 5 |
| Number Of Permutations | 190 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.1 |
| p-value | 0.666 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 16 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | -0.192 |
| p-value | 0.586 |