General Structure Information 2rd0 PIK3CA structure of a human p110alpha/p85alpha complex 3.05Å AUTH C.H.HUANG,D.MANDELKER,O.SCHMIDT-KITTLER,Y.SAMUELS,AUTH 2 V.E.VELCULESCU,K.W.KINZLER,B.VOGELSTEIN,S.B.GABELLI,AUTH 3 L.M.AMZELTITL THE STRUCTURE OF A HUMAN P110ALPHA/P85ALPHA COMPLEXTITL 2 ELUCIDATES THE EFFECTS OF ONCOGENIC PI3KALPHA MUTATIONS.REF SCIENCE V. 318 1744 2007REFN ISSN 0036-8075PMID 18079394DOI 10.1126/SCIENCE.1150799 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1axc PCNA human pcna 2.6Å AUTH J.M.GULBIS,Z.KELMAN,J.HURWITZ,M.ODONNELL,J.KURIYANTITL STRUCTURE OF THE C-TERMINAL REGION OFTITL 2 P21(WAF1/CIP1) COMPLEXED WITH HUMAN PCNA.REF CELL(CAMBRIDGE,MASS.) V. 87 297 1996REFN ISSN 0092-8674PMID 8861913DOI 10.1016/S0092-8674(00)81347-1 Variant Set Distributions Mapped Variants
General Structure Information 4e93 FES crystal structure of human feline sarcoma viral oncogene homologue (v- fes)in complex with tae684 1.84Å AUTH S.HELLWIG,C.V.MIDUTURU,S.KANDA,J.ZHANG,P.FILIPPAKOPOULOS,AUTH 2 E.SALAH,X.DENG,H.G.CHOI,W.ZHOU,W.HUR,S.KNAPP,N.S.GRAY,AUTH 3 T.E.SMITHGALLTITL SMALL-MOLECULE INHIBITORS OF THE C-FES PROTEIN-TYROSINETITL 2 KINASE.REF CHEM.BIOL. V. 19 529 2012REFN ISSN 1074-5521PMID 22520759DOI 10.1016/J.CHEMBIOL.2012.01.020 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 4adf CSF1 crystal structure of the human colony-stimulating factor 1 (hcsf-1) cytokine in complex with the viral receptor barf1 4.4Å AUTH J.ELEGHEERT,N.BRACKE,P.POULIOT,I.GUTSCHE,A.V.SHKUMATOV,AUTH 2 N.TARBOURIECH,K.VERSTRAETE,A.BEKAERT,W.P.BURMEISTER,AUTH 3 D.I.SVERGUN,B.N.LAMBRECHT,B.VERGAUWEN,S.N.SAVVIDESTITL ALLOSTERIC COMPETITIVE INACTIVATION OF HEMATOPOIETIC CSF-1TITL 2 SIGNALING BY THE VIRAL DECOY RECEPTOR BARF1.REF NAT.STRUCT.MOL.BIOL. V. 19 938 2012REFN ISSN 1545-9993PMID 22902366DOI 10.1038/NSMB.2367 Variant Set Distributions […]
General Structure Information 3con NRAS crystal structure of the human nras gtpase bound with gdp 1.65Å AUTH L.NEDYALKOVA,Y.TONG,W.TEMPEL,L.SHEN,P.LOPPNAU,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE HUMAN NRAS GTPASE BOUNDTITL 2 WITH GDP.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1nkp MYC crystal structure of myc-max recognizing dna 1.8Å AUTH S.K.NAIR,S.K.BURLEYTITL X-RAY STRUCTURES OF MYC-MAX AND MAD-MAXTITL 2 RECOGNIZING DNA: MOLECULAR BASES OF REGULATION BYTITL 3 PROTO-ONCOGENIC TRANSCRIPTION FACTORSREF CELL(CAMBRIDGE,MASS.) V. 112 193 2003REFN ISSN 0092-8674PMID 12553908DOI 10.1016/S0092-8674(02)01284-9 Variant Set Distributions Mapped Variants