Assessment of Structural Intolerance and Durability
General Structure Information 1tuz DGKA nmr structure of the diacylglycerol kinase alpha, nesgc target hr532 -1.0Å AUTH G.LIU,Y.SHAO,R.XIAO,T.ACTON,G.T.MONTELIONE,AUTH 2 T.SZYPERSKITITL NMR STRUCTURE OF DIACYLGLYCEROL KINASE ALPHA,TITL 2 NESGC TARGET HR532REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3uf1 VIM crystal structure of vimentin (fragment 144-251) from homo sapiens, northeast structural genomics consortium target hr4796b 2.81Å AUTH A.AZIZ,J.F.HESS,M.S.BUDAMAGUNTA,J.C.VOSS,A.P.KUZIN,AUTH 2 Y.J.HUANG,R.XIAO,G.T.MONTELIONE,P.G.FITZGERALD,J.F.HUNTTITL THE STRUCTURE OF VIMENTIN LINKER 1 AND ROD 1B DOMAINSTITL 2 CHARACTERIZED BY SITE-DIRECTED SPIN-LABELING ELECTRONTITL 3 PARAMAGNETIC RESONANCE (SDSL-EPR) AND X-RAY CRYSTALLOGRAPHY.REF J.BIOL.CHEM. V. 287 28349 2012REFN ISSN 0021-9258PMID […]
General Structure Information 2keo HERC2 solution nmr structure of human protein hs00059, cytochrome-b5-like domain of the herc2 e3 ligase. northeast structural genomics consortium (nesg) target ht98a -1.0Å AUTH A.LEMAK,A.GUTMANAS,C.FARES,H.QUYANG,Y.LI,G.MONTELIONE,AUTH 2 C.ARROWSMITH,S.DHE-PAGANONTITL SOLUTION NMR STRUCTURE OF HUMAN PROTEIN HS00059REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3sdl ISG15 crystal structure of human isg15 in complex with ns1 n-terminal region from influenza b virus, northeast structural genomics consortium target ids hx6481, hr2873, and or2 2.29Å AUTH R.GUAN,L.C.MA,P.G.LEONARD,B.R.AMER,H.SRIDHARAN,C.ZHAO,AUTH 2 R.M.KRUG,G.T.MONTELIONETITL STRUCTURAL BASIS FOR THE SEQUENCE-SPECIFIC RECOGNITION OFTITL 2 HUMAN ISG15 BY THE NS1 PROTEIN OF INFLUENZA B VIRUS.REF PROC.NATL.ACAD.SCI.USA V. […]
General Structure Information 2kl7 EFEMP2 solution nmr structure of the egf-like 1 domain of human fibulin-4. northeast structural genomics target hr6275 -1.0Å AUTH P.ROSSI,Y.CHIANG,S.ANDERSON,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF THE EGF-LIKE 1 DOMAIN OFTITL 2 HUMAN FIBULIN-4. NORTHEAST STRUCTURAL GENOMICSTITL 3 TARGET HR6275REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3lrq TRIM37 crystal structure of the u-box domain of human ubiquitin- protein ligase (e3), northeast structural genomics consortium target hr4604d. 2.29Å AUTH A.KUZIN,Y.CHEN,J.SEETHARAMAN,M.MAO,R.XIAO,AUTH 2 C.CICCOSANTI,R.SHASTRY,J.K.EVERETT,R.NAIR,AUTH 3 T.B.ACTON,B.ROST,G.T.MONTELIONE,L.TONG,J.F.HUNTTITL E3 UBIQUITIN-PROTEIN LIGASE RING DOMAIN FROM HUMANTITL 2 TRIPARTITE MOTIF-CONTAINING PROTEIN 37 (TRIM37),TITL 3 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGETTITL 4 HR4604D.REF TO BE PUBLISHEDREFN Variant […]
General Structure Information 3rru TOM1L1 x-ray crystal structure of the vhs domain of human tom1-like protein, northeast structural genomics consortium target hr3050e 3.0Å AUTH F.FOROUHAR,S.LEW,J.SEETHARAMAN,H.WANG,C.CICCOSANTI,D.PATEL,AUTH 2 T.B.ACTON,R.XIAO,J.K.EVERETT,G.T.MONTELIONE,J.F.HUNT,L.TONGTITL X-RAY CRYSTAL STRUCTURE OF THE VHS DOMAIN OF HUMAN TOM1-LIKETITL 2 PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGETTITL 3 HR3050EREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2qs9 RBBP9 crystal structure of the human retinoblastoma-binding protein 9 (rbbp-9). nesg target hr2978 1.72Å AUTH S.M.VOROBIEV,M.SU,J.SEETHARAMAN,Y.J.HUANG,C.X.CHEN,AUTH 2 M.MAGLAQUI,H.JANJUA,M.PROUDFOOT,A.YAKUNIN,R.XIAO,AUTH 3 T.B.ACTON,G.T.MONTELIONE,L.TONGTITL CRYSTAL STRUCTURE OF HUMAN RETINOBLASTOMA BINDINGTITL 2 PROTEIN 9.REF PROTEINS V. 74 526 2008REFN ISSN 0887-3585PMID 19004028DOI 10.1002/PROT.22278 Variant Set Distributions Mapped Variants
General Structure Information 2mk2 INPPL1 solution nmr structure of n-terminal domain (sh2 domain) of human inositol polyphosphate phosphatase-like protein 1 (inppl1) (fragment 20-117), northeast structural genomics consortium target hr9134a -1.0Å AUTH Y.YANG,T.A.RAMELOT,H.JANJUA,R.XIAO,J.K.EVERETT,AUTH 2 G.T.MONTELIONE,M.A.KENNEDYTITL SOLUTION NMR STRUCTURE OF N-TERMINAL DOMAIN (SH2 DOMAIN) OFTITL 2 HUMAN INOSITOL POLYPHOSPHATE PHOSPHATASE-LIKE PROTEIN 1TITL 3 (INPPL1) (FRAGMENT 20-117), NORTHEAST […]
General Structure Information 3mtt PIK3R2 crystal structure of ish2 domain of human p85beta, northeast structural genomics consortium target hr5531c 3.3Å AUTH C.SCHAUDER,L.C.MA,R.M.KRUG,G.T.MONTELIONE,R.GUANTITL STRUCTURE OF THE ISH2 DOMAIN OF HUMAN PHOSPHATIDYLINOSITOLTITL 2 3-KINASE P85BETA SUBUNIT REVEALS CONFORMATIONAL PLASTICITYTITL 3 IN THE INTERHELICAL TURN REGIONREF ACTA CRYSTALLOGR.,SECT.F V. 66 1567 2010REFN ESSN 1744-3091PMID 21139197DOI 10.1107/S1744309110041333 Variant Set […]