Assessment of Structural Intolerance and Durability
General Structure Information 1×51 MUTYH solution structure of the nudix domain from human a/g- specific adenine dna glycosylase alpha-3 splice isoform -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE NUDIX DOMAIN FROM HUMANTITL 2 A/G-SPECIFIC ADENINE DNA GLYCOSYLASE ALPHA-3TITL 3 SPLICE ISOFORMREF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ej8 APPL1 crystal structure of appl1 ptb domain at 1.8a 1.84Å AUTH H.TANABE,T.HOSAKA,K.MURAYAMA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL CRYSTAL STRUCTURE OF APPL1 PTB DOMAIN AT 1.8AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ebw REV1 solution structure of the brct domain from human dna repair protein rev1 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE BRCT DOMAIN FROM HUMANTITL 2 DNA REPAIR PROTEIN REV1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ee3 COL20A1 solution structures of the fn3 domain of human collagen alpha-1(xx) chain -1.0Å AUTH M.SATO,N.TOCHIO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE FN3 DOMAIN OF HUMANTITL 2 COLLAGEN ALPHA-1(XX) CHAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dzj TECR 2dzj/solution structure of the n-terminal ubiquitin-like domain in human synaptic glycoprotein sc2 -1.0Å AUTH C.ZHAO,M.YONEYAMA,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL 2DZJ/SOLUTION STRUCTURE OF THE N-TERMINALTITL 2 UBIQUITIN-LIKE DOMAIN IN HUMAN SYNAPTICTITL 3 GLYCOPROTEIN SC2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dn6 SWAP70 solution structure of the ph domain of kiaa0640 protein from human -1.0Å AUTH H.LI,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OF KIAA0640TITL 2 PROTEIN FROM HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2da0 ASAP1 solution structure of the ph domain of pip2-dependent arf1 gtpase-activating protein from human -1.0Å AUTH H.LI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OFTITL 2 PIP2-DEPENDENT ARF1 GTPASE-ACTIVATING PROTEIN FROMTITL 3 HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ct6 SH3BGRL2 solution structure of the sh3 domain-binding glutamic acid- rich-like protein 2 -1.0Å AUTH K.MIYAMOTO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN-BINDINGTITL 2 GLUTAMIC ACID-RICH-LIKE PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dhz RAPGEFL1 solution structure of the ra domain in the human link guanine nucleotide exchange factor ii (link-gefii) -1.0Å AUTH C.ZHAO,T.KIGAWA,M.YONEYAMA,S.KOSHIBA,T.HARADA,AUTH 2 S.WATANABE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RA DOMAIN IN THE HUMANTITL 2 LINK GUANINE NUCLEOTIDE EXCHANGE FACTOR IITITL 3 (LINK-GEFII)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2csk SNX12 solution structure of px domain from human snx12 -1.0Å AUTH T.SUETAKE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF PX DOMAIN FROM HUMAN SNX12REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants