General Structure Information
| PDB ID | 2ct6 |
| HGNC Gene Label(s) | SH3BGRL2 |
| Structure Name | solution structure of the sh3 domain-binding glutamic acid- rich-like protein 2 |
| Resolution | -1.0Å |
| Reference | AUTH K.MIYAMOTO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN-BINDINGTITL 2 GLUTAMIC ACID-RICH-LIKE PROTEIN 2REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 98 |
| Number Of SNVs | 25 |
| Number Of Permutations | 1330 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.137 |
| p-value | 0.872 |
COSMIC
| Number Of Residues | 98 |
| Number Of SNVs | 3 |
| Number Of Permutations | 164 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.333 |
| p-value | 0.392 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 25 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | -0.257 |
| p-value | 0.603 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
