General Structure Information
| PDB ID | 1×51 |
| HGNC Gene Label(s) | MUTYH |
| Structure Name | solution structure of the nudix domain from human a/g- specific adenine dna glycosylase alpha-3 splice isoform |
| Resolution | -1.0Å |
| Reference | AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE NUDIX DOMAIN FROM HUMANTITL 2 A/G-SPECIFIC ADENINE DNA GLYCOSYLASE ALPHA-3TITL 3 SPLICE ISOFORMREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 142 |
| Number Of SNVs | 42 |
| Number Of Permutations | 18504 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.095 |
| p-value | 0.673 |
ClinVar
| Number Of Residues | 142 |
| Number Of SNVs | 3 |
| Number Of Permutations | 154 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.333 |
| p-value | 0.548 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 42 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.238 |
| p-value | 0.539 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
