Assessment of Structural Intolerance and Durability
General Structure Information 2ct2 TRIM32 solution structure of the ring domain of the tripartite motif protein 32 -1.0Å AUTH K.MIYAMOTO,N.TOCHIO,M.SATO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RING DOMAIN OF THETITL 2 TRIPARTITE MOTIF PROTEIN 32REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1xdv SOS1 experimentally phased structure of human the son of sevenless protein at 4.1 ang. 4.1Å AUTH H.SONDERMANN,S.M.SOISSON,S.BOYKEVISCH,S.S.YANG,AUTH 2 D.BAR-SAGI,J.KURIYANTITL STRUCTURAL ANALYSIS OF AUTOINHIBITION IN THE RASTITL 2 ACTIVATOR SON OF SEVENLESS.REF CELL(CAMBRIDGE,MASS.) V. 119 393 2004REFN ISSN 0092-8674PMID 15507210DOI 10.1016/J.CELL.2004.10.005 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 2cpe EWSR1 solution structure of the rna recognition motif of ewing sarcoma(ews) protein -1.0Å AUTH T.NAGATA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA RECOGNITION MOTIF OFTITL 2 EWING SARCOMA(EWS) PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2nlw EIF3B solution structure of the rrm domain of human eukaryotic initiation factor 3b -1.0Å AUTH L.ELANTAK,A.G.TZAKOS,N.LOCKER,P.J.LUKAVSKYTITL STRUCTURE OF EIF3B RNA RECOGNITION MOTIF AND ITSTITL 2 INTERACTION WITH EIF3J: STRUCTURAL INSIGHTS INTOTITL 3 THE RECRUITMENT OF EIF3B TO THE 40 S RIBOSOMALTITL 4 SUBUNIT.REF J.BIOL.CHEM. V. 282 8165 2007REFN ISSN 0021-9258PMID 17190833DOI […]
General Structure Information 4iyp IGBP1 structure of the npp2ac-alpha4 complex 2.8Å AUTH L.JIANG,V.STANEVICH,K.A.SATYSHUR,M.KONG,G.R.WATKINS,AUTH 2 B.E.WADZINSKI,R.SENGUPTA,Y.XINGTITL STRUCTURAL BASIS OF PROTEIN PHOSPHATASE 2A STABLE LATENCY.REF NAT COMMUN V. 4 1699 2013REFN ESSN 2041-1723PMID 23591866DOI 10.1038/NCOMMS2663 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1hp8 CMC4 solution structure of human p8-mtcp1, a cysteine-rich protein encoded by the mtcp1 oncogene,reveals a new alpha- helical assembly motif, nmr, minimized average structure -1.0Å AUTH P.BARTHE,Y.S.YANG,L.CHICHE,F.HOH,M.P.STRUB,AUTH 2 L.GUIGNARD,J.SOULIER,M.H.STERN,H.VAN TILBEURGH,AUTH 3 J.M.LHOSTE,C.ROUMESTANDTITL SOLUTION STRUCTURE OF HUMAN P8MTCP1, ATITL 2 CYSTEINE-RICH PROTEIN ENCODED BY THE MTCP1TITL 3 ONCOGENE, REVEALS A NEW ALPHA-HELICAL […]
General Structure Information 1zy7 ADARB1 crystal structure of the catalytic domain of an adenosine deaminase that acts on rna (hadar2) bound to inositol hexakisphosphate (ihp) 1.7Å AUTH M.R.MACBETH,H.L.SCHUBERT,A.P.VANDEMARK,A.T.LINGAM,AUTH 2 C.P.HILL,B.L.BASSTITL INOSITOL HEXAKISPHOSPHATE IS BOUND IN THE ADAR2TITL 2 CORE AND REQUIRED FOR RNA EDITING.REF SCIENCE V. 309 1534 2005REFN ISSN 0036-8075PMID 16141067DOI 10.1126/SCIENCE.1113150 Variant Set […]
General Structure Information 1dt4 NOVA1 crystal structure of nova-1 kh3 k-homology rna-binding domain 2.6Å AUTH H.A.LEWIS,H.CHEN,C.EDO,R.J.BUCKANOVICH,Y.Y.YANG,AUTH 2 K.MUSUNURU,R.ZHONG,R.B.DARNELL,S.K.BURLEYTITL CRYSTAL STRUCTURES OF NOVA-1 AND NOVA-2 K-HOMOLOGYTITL 2 RNA-BINDING DOMAINS.REF STRUCTURE FOLD.DES. V. 7 191 1999REFN ISSN 0969-2126PMID 10368286DOI 10.1016/S0969-2126(99)80025-2 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2do0 HNRNPM solution structure of the rna binding domain of heterogeneous nuclear ribonucleoprotein m -1.0Å AUTH S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA BINDING DOMAIN OFTITL 2 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN MREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2hgm HNRNPF nmr structure of the second qrrm domain of human hnrnp f -1.0Å AUTH C.DOMINGUEZ,F.H.ALLAINTITL NMR STRUCTURE OF THE THREE QUASI RNA RECOGNITIONTITL 2 MOTIFS (QRRMS) OF HUMAN HNRNP F AND INTERACTIONTITL 3 STUDIES WITH BCL-X G-TRACT RNA: A NOVEL MODE OFTITL 4 RNA RECOGNITION.REF NUCLEIC ACIDS RES. V. 34 3634 […]