General Structure Information
| PDB ID | 1dt4 |
| HGNC Gene Label(s) | NOVA1 |
| Structure Name | crystal structure of nova-1 kh3 k-homology rna-binding domain |
| Resolution | 2.6Å |
| Reference | AUTH H.A.LEWIS,H.CHEN,C.EDO,R.J.BUCKANOVICH,Y.Y.YANG,AUTH 2 K.MUSUNURU,R.ZHONG,R.B.DARNELL,S.K.BURLEYTITL CRYSTAL STRUCTURES OF NOVA-1 AND NOVA-2 K-HOMOLOGYTITL 2 RNA-BINDING DOMAINS.REF STRUCTURE FOLD.DES. V. 7 191 1999REFN ISSN 0969-2126PMID 10368286DOI 10.1016/S0969-2126(99)80025-2 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 72 |
| Number Of SNVs | 10 |
| Number Of Permutations | 1685 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.067 |
| p-value | 0.742 |
COSMIC
| Number Of Residues | 72 |
| Number Of SNVs | 4 |
| Number Of Permutations | 87 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 10 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.267 |
| p-value | 0.664 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
