Assessment of Structural Intolerance and Durability
General Structure Information 4nj4 ALKBH5 crystal structure of human alkbh5 2.02Å AUTH W.AIK,J.S.SCOTTI,H.CHOI,L.GONG,M.DEMETRIADES,C.J.SCHOFIELD,AUTH 2 M.A.MCDONOUGHTITL STRUCTURE OF HUMAN RNA N6-METHYLADENINE DEMETHYLASE ALKBH5TITL 2 PROVIDES INSIGHTS INTO ITS MECHANISMS OF NUCLEIC ACIDTITL 3 RECOGNITION AND DEMETHYLATION.REF NUCLEIC ACIDS RES. V. 42 4741 2014REFN ISSN 0305-1048PMID 24489119DOI 10.1093/NAR/GKU085 Variant Set Distributions Mapped Variants
General Structure Information 3eij PDCD4 crystal structure of pdcd4 2.8Å AUTH P.G.LOH,H.-S.YANG,M.A.WALSH,Q.WANG,X.WANG,Z.CHENG,D.LIU,AUTH 2 H.SONGTITL STRUCTURAL BASIS FOR TRANSLATIONAL INHIBITION BY THE TUMOURTITL 2 SUPPRESSOR PDCD4REF EMBO J. V. 28 274 2009REFN ISSN 0261-4189PMID 19153607DOI 10.1038/EMBOJ.2008.278 Variant Set Distributions Mapped Variants
General Structure Information 3i8e DDB1 crystal structure of ddb1 in complex with the h-box motif of wdr42a 3.4Å AUTH T.LI,E.I.ROBERT,P.C.VAN BREUGEL,M.STRUBIN,N.ZHENGTITL A PROMISCUOUS ALPHA-HELICAL MOTIF ANCHORS VIRAL HIJACKERSTITL 2 AND SUBSTRATE RECEPTORS TO THE CUL4-DDB1 UBIQUITIN LIGASETITL 3 MACHINERY.REF NAT.STRUCT.MOL.BIOL. V. 17 105 2010REFN ISSN 1545-9993PMID 19966799DOI 10.1038/NSMB.1719 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3i7p DCAF12 crystal structure of ddb1 in complex with the h-box motif of wdr40a 3.0Å AUTH T.LI,E.I.ROBERT,P.C.VAN BREUGEL,M.STRUBIN,N.ZHENGTITL A PROMISCUOUS ALPHA-HELICAL MOTIF ANCHORS VIRALTITL 2 HIJACKERS AND SUBSTRATE RECEPTORS TO THE CUL4-DDB1TITL 3 UBIQUITIN LIGASE MACHINERY.REF NAT.STRUCT.MOL.BIOL. V. 17 105 2010REFN ISSN 1545-9993PMID 19966799DOI 10.1038/NSMB.1719 Variant Set Distributions Mapped Variants
General Structure Information 3kb5 TRIM72 pry-spry domain of human trim72 1.5Å AUTH E.Y.PARK,O.-B.KWON,B.-C.JEONG,J.-S.YI,C.S.LEE,AUTH 2 Y.-G.KO,H.K.SONGTITL CRYSTAL STRUCTURE OF PRY-SPRY DOMAIN OF HUMANTITL 2 TRIM72REF PROTEINS 2009REFN ESSN 1097-0134PMID 19967786DOI 10.1002/PROT.22647 Variant Set Distributions Mapped Variants
General Structure Information 3ch4 PMVK the crystal structure of human phosphomavelonate kinase at 1.8 a resolution 1.76Å AUTH Q.CHANG,X.-X.YAN,S.-Y.GU,J.-F.LIU,D.-C.LIANGTITL CRYSTAL STRUCTURE OF HUMAN PHOSPHOMAVELONATETITL 2 KINASE AT 1.8 A RESOLUTIONREF PROTEINS V. 73 254 2008REFN ISSN 0887-3585PMID 18618710DOI 10.1002/PROT.22151 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2csv TRIM29 solution structure of the zf-b_box type2 domain of human tripartite motif protein trim29 isoform alpha -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-B_BOX TYPE2 DOMAIN OFTITL 2 HUMAN TRIPARTITE MOTIF PROTEIN TRIM29 ISOFORM ALPHAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2csv TRIM29 solution structure of the zf-b_box type2 domain of human tripartite motif protein trim29 isoform alpha -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-B_BOX TYPE2 DOMAIN OFTITL 2 HUMAN TRIPARTITE MOTIF PROTEIN TRIM29 ISOFORM ALPHAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2csv TRIM29 solution structure of the zf-b_box type2 domain of human tripartite motif protein trim29 isoform alpha -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-B_BOX TYPE2 DOMAIN OFTITL 2 HUMAN TRIPARTITE MOTIF PROTEIN TRIM29 ISOFORM ALPHAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2csv TRIM29 solution structure of the zf-b_box type2 domain of human tripartite motif protein trim29 isoform alpha -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-B_BOX TYPE2 DOMAIN OFTITL 2 HUMAN TRIPARTITE MOTIF PROTEIN TRIM29 ISOFORM ALPHAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants