Assessment of Structural Intolerance and Durability
General Structure Information 2p57 ARFGAP2 gap domain of znf289, an id1-regulated zinc finger protein 1.8Å AUTH Y.TONG,S DIMOV,L.SHEN,H.ZHU,W.TEMPEL,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL GAP DOMAIN OF ZNF289, AN ID1-REGULATED ZINC FINGERTITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4aqi S100A7A structure of human s100a15 bound to zinc and calcium 1.7Å AUTH J.I.MURRAY,M.L.TONKIN,A.L.WHITING,F.PENG,B.FARNELL,AUTH 2 J.T.CULLEN,F.HOF,M.J.BOULANGERTITL STRUCTURAL CHARACTERIZATION OF S100A15 REVEALS A NOVEL ZINCTITL 2 COORDINATION SITE AMONG S100 PROTEINS AND ALTERED SURFACETITL 3 CHEMISTRY WITH FUNCTIONAL IMPLICATIONS FOR RECEPTORTITL 4 BINDING.REF BMC STRUCT.BIOL. V. 12 16 2012REFN ISSN 1472-6807PMID 22747601DOI 10.1186/1472-6807-12-16 […]
General Structure Information 2b0o ASAP3 crystal structure of uplc1 gap domain 2.06Å AUTH S.ISMAIL,L.SHEN,C.ARROWSMITH,A.EDWARDS,M.SUNDSTROM,AUTH 2 J.WEIGELT,A.BOCHKAREV,H.PARKTITL STRUCTURAL ANALYSIS OF GAP AND ANKYRIN DOMAINS OFTITL 2 UPLC1REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2lt7 ZBTB33 solution nmr structure of kaiso zinc finger dna binding domain in complex with kaiso binding site dna -1.0Å AUTH B.A.BUCK-KOEHNTOP,R.L.STANFIELD,D.C.EKIERT,AUTH 2 M.A.MARTINEZ-YAMOUT,H.J.DYSON,I.A.WILSON,P.E.WRIGHTTITL MOLECULAR BASIS FOR RECOGNITION OF METHYLATED AND SPECIFICTITL 2 DNA SEQUENCES BY THE ZINC FINGER PROTEIN KAISO.REF PROC.NATL.ACAD.SCI.USA V. 109 15229 2012REFN ISSN 0027-8424PMID 22949637DOI 10.1073/PNAS.1213726109 Variant Set […]
General Structure Information 2co8 MICAL1 solution structures of the lim domain of human nedd9 interacting protein with calponin homology and lim domains -1.0Å AUTH M.SATO,T.TOMIZAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE LIM DOMAIN OF HUMANTITL 2 NEDD9 INTERACTING PROTEIN WITH CALPONIN HOMOLOGYTITL 3 AND LIM DOMAINSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1ekg FXN mature human frataxin 1.8Å AUTH S.DHE-PAGANON,R.SHIGETA,Y.I.CHI,M.RISTOW,AUTH 2 S.E.SHOELSONTITL CRYSTAL STRUCTURE OF HUMAN FRATAXIN.REF J.BIOL.CHEM. V. 275 30753 2000REFN ISSN 0021-9258PMID 10900192DOI 10.1074/JBC.C000407200 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4iy3 CNNM4 structural and ligand binding properties of the bateman domain of human magnesium transporters cnnm2 and cnnm4 3.6Å AUTH M.A.CORRAL-RODRIGUEZ,M.STUIVER,J.A.ENCINAR,V.SPIWOK,AUTH 2 I.GOMEZ-GARCIA,I.OYENARTE,J.ERENO-ORBEA,H.TERASHIMA,AUTH 3 A.ACCARDI,T.DIERCKS,D.MULLER,L.A.MARTINEZ-CRUZTITL STRUCTURAL AND LIGAND BINDING PROPERTIES OF THE BATEMANTITL 2 DOMAIN OF HUMAN MAGNESIUM TRANSPORTERS CNNM2 AND CNNM4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2d8s MARCH8 solution structure of the ring domain of the human cellular modulator of immune recognition protein -1.0Å AUTH K.MIYAMOTO,T.KIGAWA,T.TOMIZAWA,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RING DOMAIN OF THE HUMANTITL 2 CELLULAR MODULATOR OF IMMUNE RECOGNITION PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 1de4 HFE hemochromatosis protein hfe complexed with transferrin receptor 2.8Å AUTH M.J.BENNETT,J.A.LEBRON,P.J.BJORKMANTITL CRYSTAL STRUCTURE OF THE HEREDITARY HAEMOCHROMATOSIS PROTEINTITL 2 HFE COMPLEXED WITH TRANSFERRIN RECEPTOR.REF NATURE V. 403 46 2000REFN ISSN 0028-0836PMID 10638746DOI 10.1038/47417 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2rn9 COX17 solution structure of human apocox17 -1.0Å AUTH L.BANCI,I.BERTINI,S.CIOFI-BAFFONI,A.JANICKA,AUTH 2 M.MARTINELLI,H.KOZLOWSKI,P.PALUMAATITL A STRUCTURAL-DYNAMICAL CHARACTERIZATION OF HUMANTITL 2 COX17REF J.BIOL.CHEM. V. 283 7912 2008REFN ISSN 0021-9258PMID 18093982DOI 10.1074/JBC.M708016200 Variant Set Distributions Mapped Variants