Assessment of Structural Intolerance and Durability
General Structure Information 2jc2 SRI the crystal structure of the natural f112l human sorcin mutant 2.5Å AUTH S.FRANCESCHINI,A.ILARI,D.VERZILI,C.ZAMPARELLI,AUTH 2 A.ANTARAMIAN,A.RUEDA,H.H.VALDIVIA,E.CHIANCONE,AUTH 3 G.COLOTTITITL MOLECULAR BASIS FOR THE IMPAIRED FUNCTION OF THETITL 2 NATURAL F112L SORCIN MUTANT: X-RAY CRYSTALTITL 3 STRUCTURE, CALCIUM AFFINITY, AND INTERACTION WITHTITL 4 ANNEXIN VII AND THE RYANODINE RECEPTOR.REF FASEB J. V. 22 […]
General Structure Information 3q8k FEN1 crystal structure of human flap endonuclease fen1 (wt) in complex with product 5-flap dna, sm3+, and k+ 2.2Å AUTH S.E.TSUTAKAWA,S.CLASSEN,B.R.CHAPADOS,A.S.ARVAI,L.D.FINGER,AUTH 2 G.GUENTHER,C.G.TOMLINSON,P.THOMPSON,A.H.SARKER,B.SHEN,AUTH 3 P.K.COOPER,J.A.GRASBY,J.A.TAINERTITL HUMAN FLAP ENDONUCLEASE STRUCTURES, DNA DOUBLE-BASETITL 2 FLIPPING, AND A UNIFIED UNDERSTANDING OF THE FEN1TITL 3 SUPERFAMILY.REF CELL(CAMBRIDGE,MASS.) V. 145 198 2011REFN ISSN 0092-8674PMID 21496641DOI 10.1016/J.CELL.2011.03.004 […]
General Structure Information 2d8n RCVRN crystal structure of human recoverin at 2.2 a resolution 2.2Å AUTH S.KAMO,S.KISHISHITA,K.MURAYAMA,M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF HUMAN RECOVERIN AT 2.2 A RESOLUTIONREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2koy ATP7B structure of the e1064a mutant of the n-domain of wilson disease associated protein -1.0Å AUTH O.Y.DMITRIEV,S.L.LUTSENKO,E.E.UHLEMANNTITL THE STRUCTURE OF THE E1064A MUTANT REVEALS ATP-DEPENDENTTITL 2 CONFORMATIONAL CHANGES IN THE ATP7B N-DOMAIN.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2luc S100A11 solution structure of human s100 calcium-binding protein a11 -1.0Å AUTH K.W.HUNG,Y.M.CHANG,C.YUTITL NMR STRUCTURE NOTE: THE STRUCTURE OF HUMAN CALCIUM-BOUNDTITL 2 S100A11.REF J.BIOMOL.NMR V. 54 211 2012REFN ISSN 0925-2738PMID 22903637DOI 10.1007/S10858-012-9661-2 Variant Set Distributions Mapped Variants
General Structure Information 3fe4 CA6 crystal structure of human carbonic anhydrase vi 1.9Å AUTH E.S.PILKA,G.KOCHAN,U.OPPERMANN,W.W.YUETITL CRYSTAL STRUCTURE OF THE SECRETORY ISOZYME OF MAMMALIANTITL 2 CARBONIC ANHYDRASES CA VI: IMPLICATIONS FOR BIOLOGICALTITL 3 ASSEMBLY AND INHIBITOR DEVELOPMENTREF BIOCHEM.BIOPHYS.RES.COMMUN. V. 419 485 2012REFN ISSN 0006-291XPMID 22366092DOI 10.1016/J.BBRC.2012.02.038 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1ggz CALML3 crystal structure of the calmodulin-like protein (hclp) from human epithelial cells 1.5Å AUTH B.G.HAN,M.HAN,H.SUI,P.YASWEN,P.J.WALIAN,B.K.JAPTITL CRYSTAL STRUCTURE OF HUMAN CALMODULIN-LIKETITL 2 PROTEIN: INSIGHTS INTO ITS FUNCTIONAL ROLE.REF FEBS LETT. V. 521 24 2002REFN ISSN 0014-5793PMID 12067719DOI 10.1016/S0014-5793(02)02780-1 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]