Assessment of Structural Intolerance and Durability
General Structure Information 2m0r S100A14 solution structure and dynamics of human s100a14 -1.0Å AUTH I.BERTINI,V.BORSI,L.CEROFOLINI,S.DAS GUPTA,M.FRAGAI,AUTH 2 C.LUCHINATTITL SOLUTION STRUCTURE AND DYNAMICS OF HUMAN S100A14.REF J.BIOL.INORG.CHEM. V. 18 183 2013REFN ISSN 0949-8257PMID 23197251DOI 10.1007/S00775-012-0963-3 Variant Set Distributions Mapped Variants
General Structure Information 3iwp CUTC crystal structure of human copper homeostasis protein cutc 2.5Å AUTH Y.LI,J.DU,P.ZHANG,J.DINGTITL CRYSTAL STRUCTURE OF HUMAN COPPER HOMEOSTASISTITL 2 PROTEIN CUTC REVEALS A POTENTIAL COPPER-BINDINGTITL 3 SITEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1x4w ZFAND3 solution structure of the zf-an1 domain from human hypothetical protein flj13222 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-AN1 DOMAIN FROM HUMANTITL 2 HYPOTHETICAL PROTEIN FLJ13222REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3d2n MBNL1 crystal structure of mbnl1 tandem zinc finger 1 and 2 domain 2.7Å AUTH M.TEPLOVA,D.J.PATELTITL STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY THETITL 2 ALTERNATIVE-SPLICING REGULATOR MUSCLEBLIND-LIKETITL 3 MBNL1.REF NAT.STRUCT.MOL.BIOL. V. 15 1343 2008REFN ISSN 1545-9993PMID 19043415DOI 10.1038/NSMB.1519 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 2xml KDM4C crystal structure of human jmjd2c catalytic domain 2.55Å AUTH L.HILLRINGHAUS,W.W.YUE,N.R.ROSE,S.S.NG,C.GILEADI,C.LOENARZ,AUTH 2 S.H.BELLO,J.E.BRAY,C.J.SCHOFIELD,U.OPPERMANNTITL STRUCTURAL AND EVOLUTIONARY BASIS FOR THE DUAL SUBSTRATETITL 2 SELECTIVITY OF HUMAN KDM4 HISTONE DEMETHYLASE FAMILY.REF J.BIOL.CHEM. V. 286 41616 2011REFN ISSN 0021-9258PMID 21914792DOI 10.1074/JBC.M111.283689 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 3fm8 KIF13B crystal structure of full length centaurin alpha-1 bound with the fha domain of kif13b (capri target) 2.3Å AUTH Y.TONG,W.TEMPEL,H.WANG,K.YAMADA,L.SHEN,G.A.SENISTERRA,AUTH 2 F.MACKENZIE,A.H.CHISHTI,H.W.PARKTITL PHOSPHORYLATION-INDEPENDENT DUAL-SITE BINDING OF THE FHATITL 2 DOMAIN OF KIF13 MEDIATES PHOSPHOINOSITIDE TRANSPORT VIATITL 3 CENTAURIN ALPHA1.REF PROC.NATL.ACAD.SCI.USA V. 107 20346 2010REFN ISSN 0027-8424PMID 21057110DOI 10.1073/PNAS.1009008107 Variant Set Distributions […]
General Structure Information 2eeh PDZD7 solution structure of first pdz domain of pdz domain containing protein 7 -1.0Å AUTH T.N.NIRAULA,N.TOCHIO,T.TOMIZAWA,K.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF FIRST PDZ DOMAIN OF PDZTITL 2 DOMAIN CONTAINING PROTEIN 7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2e30 CHP1 solution structure of the cytoplasmic region of na+/h+ exchanger 1 complexed with essential cofactor calcineurin b homologous protein 1 -1.0Å AUTH M.MISHIMA,S.WAKABAYASHI,C.KOJIMATITL SOLUTION STRUCTURE OF THE CYTOPLASMIC REGION OFTITL 2 NA+/H+ EXCHANGER 1 COMPLEXED WITH ESSENTIALTITL 3 COFACTOR CALCINEURIN B HOMOLOGOUS PROTEIN 1REF J.BIOL.CHEM. V. 282 2741 2007REFN ISSN 0021-9258PMID […]
General Structure Information 2d8r THAP2 solution structure of the thap domain of the human thap domain-containing protein 2 -1.0Å AUTH K.MIYAMOTO,T.KIGAWA,T.TOMIZAWA,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THAP DOMAIN OF THE HUMANTITL 2 THAP DOMAIN-CONTAINING PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1xcr C11orf54 crystal structure of longer splice variant of ptd012 from homo sapiens reveals a novel zinc-containing fold 1.7Å AUTH B.A.MANJASETTY,K.BUESSOW,M.FIEBER-ERDMANN,Y.ROSKE,J.GOBOM,AUTH 2 C.SCHEICH,F.GOETZ,F.H.NIESEN,U.HEINEMANNTITL CRYSTAL STRUCTURE OF HOMO SAPIENS PTD012 REVEALS ATITL 2 ZINC-CONTAINING HYDROLASE FOLDREF PROTEIN SCI. V. 15 914 2006REFN ISSN 0961-8368PMID 16522806DOI 10.1110/PS.052037006 Variant Set Distributions Mapped Variants