Assessment of Structural Intolerance and Durability
General Structure Information 3umi APP x-ray structure of the e2 domain of the human amyloid precursor protein (app) in complex with zinc 2.4Å AUTH S.O.DAHMS,I.KONNIG,D.ROESER,K.H.GUHRS,M.C.MAYER,D.KADEN,AUTH 2 G.MULTHAUP,M.E.THANTITL METAL BINDING DICTATES CONFORMATION AND FUNCTION OF THETITL 2 AMYLOID PRECURSOR PROTEIN (APP) E2 DOMAIN.REF J.MOL.BIOL. V. 416 438 2012REFN ISSN 0022-2836PMID 22245578DOI 10.1016/J.JMB.2011.12.057 Variant Set Distributions Ripley’s […]
General Structure Information 2lq6 BRD1 solution structure of brd1 phd2 finger -1.0Å AUTH L.LIU,S.QIN,J.ZHANG,P.JI,Y.SHI,J.WUTITL SOLUTION STRUCTURE OF AN ATYPICAL PHD FINGER IN BRPF2 ANDTITL 2 ITS INTERACTION WITH DNAREF J.STRUCT.BIOL. V. 180 165 2012REFN ISSN 1047-8477PMID 22820306DOI 10.1016/J.JSB.2012.06.014 Variant Set Distributions Mapped Variants
General Structure Information 1qdd REG1A crystal structure of human lithostathine to 1.3 a resolution 1.3Å AUTH V.GERBAUD,D.PIGNOL,E.LORET,J.A.BERTRAND,Y.BERLAND,AUTH 2 J.C.FONTECILLA-CAMPS,J.P.CANSELIER,N.GABAS,AUTH 3 J.M.VERDIERTITL MECHANISM OF CALCITE CRYSTAL GROWTH INHIBITION BYTITL 2 THE N-TERMINAL UNDECAPEPTIDE OF LITHOSTATHINE.REF J.BIOL.CHEM. V. 275 1057 2000REFN ISSN 0021-9258PMID 10625646DOI 10.1074/JBC.275.2.1057 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2kl7 EFEMP2 solution nmr structure of the egf-like 1 domain of human fibulin-4. northeast structural genomics target hr6275 -1.0Å AUTH P.ROSSI,Y.CHIANG,S.ANDERSON,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF THE EGF-LIKE 1 DOMAIN OFTITL 2 HUMAN FIBULIN-4. NORTHEAST STRUCTURAL GENOMICSTITL 3 TARGET HR6275REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2d8q ZMYND10 solution structure of the mynd domain of the human zinc finger mynd domain-containing protein 10 -1.0Å AUTH K.MIYAMOTO,T.KIGAWA,T.TOMIZAWA,N.TOCHIO,A.SASAGAWA,AUTH 2 S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE MYND DOMAIN OF THE HUMANTITL 2 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 10REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3zyw GLRX3 crystal structure of the first glutaredoxin domain of human glutaredoxin 3 (glrx3) 1.84Å AUTH M.VOLLMAR,C.JOHANSSON,R.COCKING,T.KROJER,J.R.C.MUNIZ,AUTH 2 K.L.KAVANAGH,F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,AUTH 3 A.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE FIRST GLUTAREDOXIN DOMAIN OF HUMANTITL 2 GLUTAREDOXIN 3 (GLRX3)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3bh7 RP2 crystal structure of the rp2-arl3 complex bound to gdp-alf4 1.9Å AUTH S.VELTEL,R.GASPER,E.EISENACHER,A.WITTINGHOFERTITL THE RETINITIS PIGMENTOSA 2 GENE PRODUCT IS ATITL 2 GTPASE-ACTIVATING PROTEIN FOR ARF-LIKE 3REF NAT.STRUCT.MOL.BIOL. V. 15 373 2008REFN ISSN 1545-9993PMID 18376416DOI 10.1038/NSMB.1396 Variant Set Distributions Mapped Variants
General Structure Information 2dj7 ABLIM3 solution structure of 3rd lim domain of actin-binding lim protein 3 -1.0Å AUTH T.N.NIRAULA,A.SASAGAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF 3RD LIM DOMAIN OFTITL 2 ACTIN-BINDING LIM PROTEIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4gul PIR study on structure and function relationships in human ferric pirin 1.8Å AUTH F.LIU,I.REHMANI,S.ESAKI,R.FU,L.CHEN,V.DE SERRANO,A.LIUTITL PIRIN IS AN IRON-DEPENDENT REDOX REGULATOR OF NF-KAPPA B.REF PROC.NATL.ACAD.SCI.USA V. 110 9722 2013REFN ISSN 0027-8424PMID 23716661DOI 10.1073/PNAS.1221743110 Variant Set Distributions Mapped Variants