Assessment of Structural Intolerance and Durability
General Structure Information 1j55 S100P the crystal structure of ca+-bound human s100p determined at 2.0a resolution by x-ray 2.0Å AUTH H.ZHANG,G.WANG,Y.DING,Z.WANG,R.BARRACLOUGH,P.S.RUDLAND,AUTH 2 D.G.FERNIG,Z.RAOTITL THE CRYSTAL STRUCTURE AT 2A RESOLUTION OF THE CA2+-BINDINGTITL 2 PROTEIN S100PREF J.MOL.BIOL. V. 325 785 2003REFN ISSN 0022-2836PMID 12507480DOI 10.1016/S0022-2836(02)01278-0 Variant Set Distributions Mapped Variants
General Structure Information 1k95 GCA crystal structure of des(1-52)grancalcin with bound calcium 1.9Å AUTH J.JIA,N.BORREGAARD,K.LOLLIKE,M.CYGLERTITL STRUCTURE OF CA(2+)-LOADED HUMAN GRANCALCIN.REF ACTA CRYSTALLOGR.,SECT.D V. 57 1843 2001REFN ISSN 0907-4449PMID 11717497DOI 10.1107/S0907444901016511 Variant Set Distributions Mapped Variants
General Structure Information 2llt S100A1 post-translational s-nitrosylation is an endogenous factor fine-tuning human s100a1 protein properties -1.0Å AUTH M.LENARCIC ZIVKOVIC,M.ZAREBA-KOZIOL,L.ZHUKOVA,J.POZNANSKI,AUTH 2 I.ZHUKOV,A.WYSLOUCH-CIESZYNSKATITL POST-TRANSLATIONAL S-NITROSYLATION IS AN ENDOGENOUS FACTORTITL 2 FINE TUNING THE PROPERTIES OF HUMAN S100A1 PROTEIN.REF J.BIOL.CHEM. V. 287 40457 2012REFN ISSN 0021-9258PMID 22989881DOI 10.1074/JBC.M112.418392 Variant Set Distributions Mapped Variants
General Structure Information 4duq S100A2 the structure of ca2+-loaded s100a2 at 1.3a resolution 1.3Å AUTH M.KOCH,G.FRITZTITL THE STRUCTURE OF CA2+-LOADED S100A2 AT 1.3- ANGSTROMTITL 2 RESOLUTION.REF FEBS J. V. 279 1799 2012REFN ISSN 1742-464XPMID 22394450DOI 10.1111/J.1742-4658.2012.08556.X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2o72 CDH1 crystal structure analysis of human e-cadherin (1-213) 2.0Å AUTH E.PARISINI,J.M.G.HIGGINS,J.-H.LIU,M.B.BRENNER,AUTH 2 J.-H.WANGTITL THE CRYSTAL STRUCTURE OF HUMAN E-CADHERIN DOMAINSTITL 2 1 AND 2, AND COMPARISON WITH OTHER CADHERINS INTITL 3 THE CONTEXT OF ADHESION MECHANISMREF J.MOL.BIOL. V. 373 401 2007REFN ISSN 0022-2836PMID 17850815DOI 10.1016/J.JMB.2007.08.011 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 1rk9 PVALB solution structure of human alpha-parvalbumin (minimized average structure) -1.0Å AUTH I.BAIG,I.BERTINI,C.DEL BIANCO,Y.K.GUPTA,Y.-M.LEE,AUTH 2 C.LUCHINAT,A.QUATTRONETITL PARAMAGNETISM-BASED REFINEMENT STRATEGY FOR THETITL 2 SOLUTION STRUCTURE OF HUMAN ALPHA-PARVALBUMINREF BIOCHEMISTRY V. 43 5562 2004REFN ISSN 0006-2960PMID 15122922DOI 10.1021/BI035879K Variant Set Distributions Mapped Variants
General Structure Information 2hyw ANXA2 human annexin a2 with calcium bound 2.1Å AUTH C.SHAO,F.ZHANG,M.M.KEMP,R.J.LINHARDT,D.M.WAISMAN,AUTH 2 J.F.HEAD,B.A.SEATONTITL CRYSTALLOGRAPHIC ANALYSIS OF CALCIUM-DEPENDENTTITL 2 HEPARIN BINDING TO ANNEXIN A2.REF J.BIOL.CHEM. V. 281 31689 2006REFN ISSN 0021-9258PMID 16882661DOI 10.1074/JBC.M604502200 Variant Set Distributions Mapped Variants
General Structure Information 2zoc ANXA4 crystal structure of recombinant human annexin iv 2.0Å AUTH M.KONNO,Y.KANEKO-KANZAKI,N.FUSHINOBU-OKUSHI,AUTH 2 K.MOCHIZUKI,E.UCHIKAWA,A.SATOH,K.AIKAWATITL THE COMPARISON OF THE LOOP STRUCTURE OF MEMBRANETITL 2 BINDING SITES BETWEEN HUMAN AND BOVINE ANNEXIN IVREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1ttx OCM solution stucture of human beta parvalbumin (oncomodulin) refined with a paramagnetism based strategy -1.0Å AUTH E.BABINI,I.BERTINI,F.CAPOZZI,C.DEL BIANCO,AUTH 2 D.HOLLENDER,T.KISS,C.LUCHINAT,A.QUATTRONETITL SOLUTION STRUCTURE OF HUMAN BETA-PARVALBUMIN ANDTITL 2 STRUCTURAL COMPARISON WITH ITS PARALOGTITL 3 ALPHA-PARVALBUMIN AND WITH THEIR RAT ORTHOLOGS(,)REF BIOCHEMISTRY V. 43 16076 2004REFN ISSN 0006-2960PMID 15610002DOI 10.1021/BI048388O Variant Set Distributions […]
General Structure Information 2h61 S100B x-ray structure of human ca2+-loaded s100b 1.9Å AUTH T.OSTENDORP,E.LECLERC,A.GALICHET,M.KOCH,N.DEMLING,B.WEIGLE,AUTH 2 C.W.HEIZMANN,P.M.KRONECK,G.FRITZTITL STRUCTURAL AND FUNCTIONAL INSIGHTS INTO RAGE ACTIVATION BYTITL 2 MULTIMERIC S100B.REF EMBO J. V. 26 3868 2007REFN ISSN 0261-4189PMID 17660747DOI 10.1038/SJ.EMBOJ.7601805 Variant Set Distributions Mapped Variants