Assessment of Structural Intolerance and Durability
General Structure Information 4din PRKAR1B novel localization and quaternary structure of the pka ri beta holoenzyme 3.7Å AUTH R.ILOUZ,J.BUBIS,J.WU,Y.Y.YIM,M.S.DEAL,A.P.KORNEV,Y.MA,AUTH 2 D.K.BLUMENTHAL,S.S.TAYLORTITL LOCALIZATION AND QUATERNARY STRUCTURE OF THE PKA RI BETATITL 2 HOLOENZYMEREF PROC.NATL.ACAD.SCI.USA V. 109 12443 2012REFN ISSN 0027-8424PMID 22797896DOI 10.1073/PNAS.1209538109 Variant Set Distributions Mapped Variants
General Structure Information 1d1j PFN2 crystal structure of human profilin ii 2.2Å AUTH I.M.NODELMAN,G.D.BOWMAN,U.LINDBERG,C.E.SCHUTTTITL X-RAY STRUCTURE DETERMINATION OF HUMAN PROFILINTITL 2 II: A COMPARATIVE STRUCTURAL ANALYSIS OF HUMANTITL 3 PROFILINS.REF J.MOL.BIOL. V. 294 1271 1999REFN ISSN 0022-2836PMID 10600384DOI 10.1006/JMBI.1999.3318 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1k6m PFKFB1 crystal structure of human liver 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2.4Å AUTH Y.H.LEE,Y.LI,K.UYEDA,C.A.HASEMANNTITL TISSUE-SPECIFIC STRUCTURE/FUNCTION DIFFERENTIATION OF THETITL 2 LIVER ISOFORM OFTITL 3 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE.REF J.BIOL.CHEM. V. 278 523 2003REFN ISSN 0021-9258PMID 12379646DOI 10.1074/JBC.M209105200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants