General Structure Information 4gs9 EPAS1 crystal structure of the high affinity heterodimer of hif2 alpha and arnt c-terminal pas domains in complex with an inactive benzoxadiazole antagonist 1.72Å AUTH J.L.ROGERS,L.BAYEH,T.H.SCHEUERMANN,J.LONGGOOD,J.KEY,AUTH 2 J.NAIDOO,L.MELITO,C.SHOKRI,D.E.FRANTZ,R.K.BRUICK,AUTH 3 K.H.GARDNER,J.B.MACMILLAN,U.K.TAMBARTITL DEVELOPMENT OF INHIBITORS OF THE PAS-B DOMAIN OF THE HIF-2TITL 2 ALPHA TRANSCRIPTION FACTORREF J.MED.CHEM. V. 56 1739 2013REFN ISSN 0022-2623PMID […]
General Structure Information 1vf6 INADL 2.1 angstrom crystal structure of the pals-1-l27n and patj l27 heterodimer complex 2.1Å AUTH Y.LI,D.KARNAK,B.DEMELER,B.MARGOLIS,A.LAVIETITL STRUCTURAL BASIS FOR L27 DOMAIN-MEDIATED ASSEMBLYTITL 2 OF SIGNALING AND CELL POLARITY COMPLEXES.REF EMBO J. V. 23 2723 2004REFN ISSN 0261-4189PMID 15241471DOI 10.1038/SJ.EMBOJ.7600294 Variant Set Distributions Mapped Variants
General Structure Information 1wao PPP5C pp5 structure 2.9Å AUTH J.YANG,S.M.ROE,M.J.CLIFF,M.A.WILLIAMS,J.E.LADBURY,AUTH 2 P.T.COHEN,D.BARFORDTITL MOLECULAR BASIS FOR TPR DOMAIN-MEDIATED REGULATIONTITL 2 OF PROTEIN PHOSPHATASE 5REF EMBO J. V. 24 1 2005REFN ISSN 0261-4189PMID 15577939DOI 10.1038/SJ.EMBOJ.7600496 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2grc SMARCA4 1.5 a structure of bromodomain from human brg1 protein, a central atpase of swi/snf remodeling complex 1.5Å AUTH M.SINGH,G.M.POPOWICZ,M.KRAJEWSKI,T.A.HOLAKTITL STRUCTURAL RAMIFICATION FOR ACETYL-LYSINETITL 2 RECOGNITION BY THE BROMODOMAIN OF HUMAN BRG1TITL 3 PROTEIN, A CENTRAL ATPASE OF THE SWI/SNFTITL 4 REMODELING COMPLEX.REF CHEMBIOCHEM V. 8 1308 2007REFN ISSN 1439-4227PMID 17582821DOI […]
General Structure Information 1s9i MAP2K2 x-ray structure of the human mitogen-activated protein kinase kinase 2 (mek2)in a complex with ligand and mgatp 3.2Å AUTH J.F.OHREN,H.CHEN,A.PAVLOVSKY,C.WHITEHEAD,E.ZHANG,AUTH 2 P.KUFFA,C.YAN,P.MCCONNELL,C.SPESSARD,C.BANOTAI,AUTH 3 W.T.MUELLER,A.DELANEY,C.OMER,J.SEBOLT-LEOPOLD,AUTH 4 D.T.DUDLEY,I.K.LEUNG,C.FLAMME,J.WARMUS,M.KAUFMAN,AUTH 5 S.BARRETT,H.TECLE,C.A.HASEMANNTITL STRUCTURES OF HUMAN MAP KINASE KINASE 1 (MEK1) ANDTITL 2 MEK2 DESCRIBE NOVEL NONCOMPETITIVE KINASETITL 3 INHIBITION.REF NAT.STRUCT.MOL.BIOL. V. 11 1192 2004REFN […]