Assessment of Structural Intolerance and Durability
General Structure Information 2ds4 TRIM45 solution structure of the filamin domain from human tripartite motif protein 45 -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FILAMIN DOMAIN FROMTITL 2 HUMAN TRIPARTITE MOTIF PROTEIN 45REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4fom PVRL3 crystal structure of human nectin-3 full ectodomain (d1-d3) 3.93Å AUTH O.J.HARRISON,J.VENDOME,J.BRASCH,X.JIN,S.HONG,P.S.KATSAMBA,AUTH 2 G.AHLSEN,R.B.TROYANOVSKY,S.M.TROYANOVSKY,B.HONIG,L.SHAPIROTITL NECTIN ECTODOMAIN STRUCTURES REVEAL A CANONICAL ADHESIVETITL 2 INTERFACE.REF NAT.STRUCT.MOL.BIOL. V. 19 906 2012REFN ISSN 1545-9993PMID 22902367DOI 10.1038/NSMB.2366 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1uem ROBO2 solution structure of the first fibronectin type iii domain of human kiaa1568 protein -1.0Å AUTH H.LI,T.KIGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST FIBRONECTIN TYPETITL 2 III DOMAIN OF HUMAN KIAA1568 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4frw PVRL4 crystal structure of human nectin-4 extracellular fragment d1-d2 3.5Å AUTH O.J.HARRISON,J.VENDOME,J.BRASCH,X.JIN,S.HONG,P.S.KATSAMBA,AUTH 2 G.AHLSEN,R.B.TROYANOVSKY,S.M.TROYANOVSKY,B.HONIG,L.SHAPIROTITL NECTIN ECTODOMAIN STRUCTURES REVEAL A CANONICAL ADHESIVETITL 2 INTERFACE.REF NAT.STRUCT.MOL.BIOL. V. 19 906 2012REFN ISSN 1545-9993PMID 22902367DOI 10.1038/NSMB.2366 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1uen NRCAM solution structure of the third fibronectin iii domain of human kiaa0343 protein -1.0Å AUTH K.MIYAMOTO,T.KIGAWA,F.HAYASHI,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD FIBRONECTIN IIITITL 2 DOMAIN OF HUMAN KIAA0343 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1uey NRCAM solution structure of the first fibronectin type iii domain of human kiaa0343 protein -1.0Å AUTH C.ZHAO,T.KIGAWA,Y.MUTO,S.KOSHIBA,N.TOCHIO,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST FIBRONECTIN TYPETITL 2 III DOMAIN OF HUMAN KIAA0343 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2frg TREML1 structure of the immunoglobulin-like domain of human tlt-1 1.19Å AUTH J.L.GATTIS,A.V.WASHINGTON,M.M.CHISHOLM,L.QUIGLEY,AUTH 2 A.SZYK,D.W.MCVICAR,J.LUBKOWSKITITL THE STRUCTURE OF THE EXTRACELLULAR DOMAIN OFTITL 2 TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLSTITL 3 LIKE TRANSCRIPT-1 AND EVIDENCE FOR A NATURALLYTITL 4 OCCURRING SOLUBLE FRAGMENT.REF J.BIOL.CHEM. V. 281 13396 2006REFN ISSN 0021-9258PMID 16505478DOI 10.1074/JBC.M600489200 Variant Set […]
General Structure Information 2dyp LILRB2 crystal structure of lilrb2(lir2/ilt4/cd85d) complexed with hla-g 2.5Å AUTH M.SHIROISHI,K.KUROKI,L.RASUBALA,K.TSUMOTO,AUTH 2 I.KUMAGAI,E.KURIMOTO,K.KATO,D.KOHDA,K.MAENAKATITL STRUCTURAL BASIS FOR RECOGNITION OF THETITL 2 NONCLASSICAL MHC MOLECULE HLA-G BY THE LEUKOCYTETITL 3 IG-LIKE RECEPTOR B2 (LILRB2/LIR2/ILT4/CD85D)REF PROC.NATL.ACAD.SCI.USA V. 103 16412 2006REFN ISSN 0027-8424PMID 17056715DOI 10.1073/PNAS.0605228103 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1ugn LILRB1 crystal structure of lir1.02, one of the alleles of lir1 1.8Å AUTH K.KUROKI,N.TSUCHIYA,M.SHIROISHI,L.RASUBALA,AUTH 2 Y.YAMASHITA,K.MATSUTA,T.FUKAZAWA,M.KUSAOI,AUTH 3 Y.MURAKAMI,M.TAKIGUCHI,T.JUJI,H.HASHIMOTO,D.KOHDA,AUTH 4 K.MAENAKA,K.TOKUNAGATITL EXTENSIVE POLYMORPHISMS OF LILRB1 (ILT2, LIR1) ANDTITL 2 THEIR ASSOCIATION WITH HLA-DRB1 SHARED EPITOPETITL 3 NEGATIVE RHEUMATOID ARTHRITIS.REF HUM.MOL.GENET. V. 14 2469 2005REFN ISSN 0964-6906PMID 16014635DOI 10.1093/HMG/DDI247 Variant Set Distributions Ripley’s […]
General Structure Information 2di7 KDELC1 solution structure of the filamin domain from human bk158_1 protein -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FILAMIN DOMAIN FROMTITL 2 HUMAN BK158_1 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants