General Structure Information 4gos VTCN1 crystal structure of human b7-h4 igv-like domain 1.59Å AUTH V.VIGDOROVICH,U.RAMAGOPAL,S.G.NATHENSON,S.C.ALMOTITL CRYSTAL STRUCTURE OF HUMAN B7-H4 IGV-LIKE DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2vgq MAVS crystal structure of human ips-1 card 2.1Å AUTH J.A.POTTER,R.E.RANDALL,G.L.TAYLORTITL CRYSTAL STRUCTURE OF HUMAN IPS-1 CASPASETITL 2 ACTIVATION RECRUITMENT DOMAINREF BMC STRUCT.BIOL. V. 8 11 2008REFN ISSN 1472-6807PMID 18307765DOI 10.1186/1472-6807-8-11 Variant Set Distributions Mapped Variants
General Structure Information 2m1w TICAM2 ticam-2 tir domain -1.0Å AUTH Y.ENOKIZONO,H.KUMETA,K.FUNAMI,M.HORIUCHI,J.SARMIENTO,AUTH 2 K.YAMASHITA,D.M.STANDLEY,M.MATSUMOTO,T.SEYA,F.INAGAKITITL STRUCTURES AND INTERFACE MAPPING OF THE TIRTITL 2 DOMAIN-CONTAINING ADAPTOR MOLECULES INVOLVED IN INTERFERONTITL 3 SIGNALING.REF PROC.NATL.ACAD.SCI.USA V. 110 19908 2013REFN ISSN 0027-8424PMID 24255114DOI 10.1073/PNAS.1222811110 Variant Set Distributions Mapped Variants
General Structure Information 2j3g FCN2 l-ficolin 2.5Å AUTH V.GARLATTI,N.BELLOY,L.MARTIN,M.LACROIX,AUTH 2 M.MATSUSHITA,Y.ENDO,T.FUJITA,J.C.FONTECILLA-CAMPS,AUTH 3 G.J.ARLAUD,N.M.THIELENS,C.GABORIAUDTITL STRUCTURAL INSIGHTS INTO THE INNATE IMMUNETITL 2 RECOGNITION SPECIFICITIES OF L- AND H-FICOLINS.REF EMBO J. V. 26 623 2007REFN ISSN 0261-4189PMID 17215869DOI 10.1038/SJ.EMBOJ.7601500 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2z7x TLR1 crystal structure of the tlr1-tlr2 heterodimer induced by binding of a tri-acylated lipopeptide 2.1Å AUTH M.S.JIN,S.E.KIM,J.Y.HEO,M.E.LEE,H.M.KIM,S.G.PAIK,H.LEE,AUTH 2 J.O.LEETITL CRYSTAL STRUCTURE OF THE TLR1-TLR2 HETERODIMER INDUCED BYTITL 2 BINDING OF A TRI-ACYLATED LIPOPEPTIDEREF CELL(CAMBRIDGE,MASS.) V. 130 1071 2007REFN ISSN 0092-8674PMID 17889651DOI 10.1016/J.CELL.2007.09.008 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 4msv FASLG crystal structure of fasl and dcr3 complex 2.5Å AUTH W.LIU,U.A.RAMAGOPAL,C.ZHAN,J.B.BONANNO,R.C.BHOSLE,AUTH 2 S.G.NATHENSON,S.C.ALMOTITL CRYSTAL STRUCTURE OF FASL AND DCR3 COMPLEXREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3dem MASP1 cub1-egf-cub2 domain of human masp-1/3 2.3Å AUTH F.TEILLET,C.GABORIAUD,M.LACROIX,L.MARTIN,G.J.ARLAUD,AUTH 2 N.M.THIELENSTITL CRYSTAL STRUCTURE OF THE CUB1-EGF-CUB2 DOMAIN OF HUMANTITL 2 MASP-1/3 AND IDENTIFICATION OF ITS INTERACTION SITES WITHTITL 3 MANNAN-BINDING LECTIN AND FICOLINSREF J.BIOL.CHEM. V. 283 25715 2008REFN ISSN 0021-9258PMID 18596036DOI 10.1074/JBC.M803551200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 4mxw LTBR structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab 3.6Å AUTH J.SUDHAMSU,J.YIN,E.Y.CHIANG,M.A.STAROVASNIK,J.L.GROGAN,AUTH 2 S.G.HYMOWITZTITL DIMERIZATION OF LT BETA R BY LT ALPHA 1 BETA 2 IS NECESSARYTITL 2 AND SUFFICIENT FOR SIGNAL TRANSDUCTION.REF PROC.NATL.ACAD.SCI.USA V. 110 19896 2013REFN ISSN 0027-8424PMID 24248355DOI 10.1073/PNAS.1310838110 Variant Set Distributions […]
General Structure Information 3e4c CASP1 procaspase-1 zymogen domain crystal strucutre 2.05Å AUTH J.M.ELLIOTT,L.ROUGE,C.WIESMANN,J.M.SCHEERTITL CRYSTAL STRUCTURE OF PROCASPASE-1 ZYMOGEN DOMAIN REVEALSTITL 2 INSIGHT INTO INFLAMMATORY CASPASE AUTOACTIVATIONREF J.BIOL.CHEM. V. 284 6546 2009REFN ISSN 0021-9258PMID 19117953DOI 10.1074/JBC.M806121200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3qwr IL12B crystal structure of il-23 in complex with an adnectin 3.25Å AUTH V.RAMAMURTHY,S.R.KRYSTEK,A.BUSH,A.WEI,S.L.EMANUEL,AUTH 2 R.DAS GUPTA,A.JANJUA,L.CHENG,M.MURDOCK,B.ABRAMCZYK,D.COHEN,AUTH 3 Z.LIN,P.MORIN,J.H.DAVIS,M.DABRITZ,D.C.MCLAUGHLIN,K.A.RUSSO,AUTH 4 G.CHAO,M.C.WRIGHT,V.A.JENNY,L.J.ENGLE,E.FURFINE,S.SHERIFFTITL STRUCTURES OF ADNECTIN/PROTEIN COMPLEXES REVEAL AN EXPANDEDTITL 2 BINDING FOOTPRINT.REF STRUCTURE V. 20 259 2012REFN ISSN 0969-2126PMID 22325775DOI 10.1016/J.STR.2011.11.016 Variant Set Distributions Mapped Variants