Assessment of Structural Intolerance and Durability
General Structure Information 2jju SIRPB1 structure of human signal regulatory protein (sirp) beta 1.19Å AUTH D.HATHERLEY,S.C.GRAHAM,J.TURNER,K.HARLOS,AUTH 2 D.I.STUART,A.N.BARCLAYTITL PAIRED RECEPTOR SPECIFICITY EXPLAINED BYTITL 2 STRUCTURES OF SIGNAL REGULATORY PROTEINS ALONE ANDTITL 3 COMPLEXED WITH CD47.REF MOL.CELL V. 31 266 2008REFN ISSN 1097-2765PMID 18657508DOI 10.1016/J.MOLCEL.2008.05.026 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 4f8t BTN3A3 crystal structure of the human btn3a3 ectodomain 2.38Å AUTH A.PALAKODETI,A.SANDSTROM,L.SUNDARESAN,C.HARLY,S.NEDELLEC,AUTH 2 D.OLIVE,E.SCOTET,M.BONNEVILLE,E.J.ADAMSTITL THE MOLECULAR BASIS FOR MODULATION OF HUMANTITL 2 V(GAMMA)9V(DELTA)2 T CELL RESPONSE BY CD277/BUTRYOPHILINTITL 3 (BTN3A)-SPECIFIC ANTIBODIESREF J.BIOL.CHEM. V. 287 32780 2012REFN ISSN 0021-9258PMID 22846996DOI 10.1074/JBC.M112.384354 Variant Set Distributions Mapped Variants
General Structure Information 2d9k TRAFD1 solution structure of the zf-traf domain of fln29 gene product -1.0Å AUTH T.SUETAKE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-TRAF DOMAIN OF FLN29TITL 2 GENE PRODUCTREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2wnp FCN1 m-ficolin mutant y271f 1.21Å AUTH E.GOUT,V.GARLATTI,D.F.SMITH,M.LACROIX,AUTH 2 C.DUMESTRE-PERARD,T.LUNARDI,L.MARTIN,J.Y.CESBRON,AUTH 3 G.J.ARLAUD,C.GABORIAUD,N.M.THIELENSTITL CARBOHYDRATE RECOGNITION PROPERTIES OF HUMANTITL 2 FICOLINS: GLYCAN ARRAY SCREENING REVEALS THETITL 3 SIALIC ACID BINDING SPECIFICITY OF M-FICOLIN.REF J.BIOL.CHEM. V. 285 6612 2010REFN ISSN 0021-9258PMID 20032467DOI 10.1074/JBC.M109.065854 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4f80 BTN3A1 crystal structure of the human btn3a1 ectodomain 1.94Å AUTH A.PALAKODETI,A.SANDSTROM,L.SUNDARESAN,C.HARLY,S.NEDELLEC,AUTH 2 D.OLIVE,E.SCOTET,M.BONNEVILLE,E.J.ADAMSTITL THE MOLECULAR BASIS FOR MODULATION OF HUMANTITL 2 V(GAMMA)9V(DELTA)2 T CELL RESPONSES BY CD277/BUTYROPHILIN-3TITL 3 (BTN3A)-SPECIFIC ANTIBODIESREF J.BIOL.CHEM. V. 287 32780 2012REFN ISSN 0021-9258PMID 22846996DOI 10.1074/JBC.M112.384354 Variant Set Distributions Mapped Variants
General Structure Information 3noi NCR3 crystal structure of natural killer cell cytotoxicity receptor nkp30 (ncr3) 1.84Å AUTH M.G.JOYCE,P.TRAN,M.A.ZHURAVLEVA,J.JAW,M.COLONNA,P.D.SUNTITL STRUCTURE OF THE NATURAL KILLER CELL ACTIVATING RECEPTORTITL 2 NKP30 AND DISSECTION OF LIGAND BINDING SITEREF PROC.NATL.ACAD.SCI.USA 2011REFN ESSN 1091-6490 Variant Set Distributions Mapped Variants
General Structure Information 2d3v LILRA5 crystal structure of leukocyte ig-like receptor a5 (lilra5/lir9/ilt11) 1.85Å AUTH M.SHIROISHI,M.KAJIKAWA,K.KUROKI,T.OSE,D.KOHDA,AUTH 2 K.MAENAKATITL CRYSTAL STRUCTURE OF THE HUMAN MONOCYTE-ACTIVATINGTITL 2 RECEPTOR,REF J.BIOL.CHEM. V. 281 19536 2006REFN ISSN 0021-9258PMID 16675463DOI 10.1074/JBC.M603076200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants