Assessment of Structural Intolerance and Durability
General Structure Information 2wfd LARS structure of the human cytosolic leucyl-trna synthetase editing domain 3.25Å AUTH E.SEIRADAKE,W.MAO,V.HERNANDEZ,S.J.BAKER,AUTH 2 J.J.PLATTNER,M.R.K.ALLEY,S.CUSACKTITL CRYSTAL STRUCTURES OF THE HUMAN AND FUNGALTITL 2 CYTOSOLIC LEUCYL-TRNA SYNTHETASE EDITING DOMAINS:TITL 3 A STRUCTURAL BASIS FOR THE RATIONAL DESIGN OFTITL 4 ANTIFUNGAL BENZOXABOROLES.REF J.MOL.BIOL. V. 390 196 2009REFN ISSN 0022-2836PMID 19426743DOI 10.1016/J.JMB.2009.04.073 Variant Set […]
General Structure Information 4i1o RAB1B crystal structure of the legionella pneumophila gap domain of lepb in complex with rab1b bound to gdp and bef3 2.7Å AUTH E.MIHAI GAZDAG,A.STRELLER,I.HANEBURGER,H.HILBI,I.R.VETTER,AUTH 2 R.S.GOODY,A.ITZENTITL MECHANISM OF RAB1B DEACTIVATION BY THE LEGIONELLATITL 2 PNEUMOPHILA GAP LEPB.REF EMBO REP. V. 14 199 2013REFN ISSN 1469-221XPMID 23288104DOI 10.1038/EMBOR.2012.211 Variant Set Distributions Ripley’s […]
General Structure Information 2atv RERG the crystal structure of human rerg in the gdp bound state 1.9Å AUTH A.P.TURNBULL,E.SALAH,G.SCHOCH,J.ELKINS,N.BURGESS,O.GILEADI,AUTH 2 F.VON DELFT,J.WEIGELT,A.EDWARDS,C.ARROWSMITH,M.SUNDSTROM,AUTH 3 D.DOYLETITL THE CRYSTAL STRUCTURE OF HUMAN RERG IN THE GDP BOUND STATEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2erx DIRAS2 crystal structure of diras2 in complex with gdp and inorganic phosphate 1.65Å AUTH E.PAPAGRIGORIOU,X.YANG,J.ELKINS,F.E.NIESEN,AUTH 2 N.BURGESS,E.SALAH,O.FEDOROV,L.J.BALL,F.VON DELFT,AUTH 3 M.SUNDSTROM,A.EDWARDS,C.ARROWSMITH,J.WEIGELT,AUTH 4 D.DOYLETITL CRYSTAL STRUCTURE OF DIRAS2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4gnk PLCB3 crystal structure of galphaq in complex with full-length human plcbeta3 4.0Å AUTH A.M.LYON,S.DUTTA,C.A.BOGUTH,G.SKINIOTIS,J.J.TESMERTITL FULL-LENGTH G ALPHA (Q)-PHOSPHOLIPASE C-BETA 3 STRUCTURETITL 2 REVEALS INTERFACES OF THE C-TERMINAL COILED-COIL DOMAIN.REF NAT.STRUCT.MOL.BIOL. V. 20 355 2013REFN ISSN 1545-9993PMID 23377541DOI 10.1038/NSMB.2497 Variant Set Distributions Mapped Variants
General Structure Information 4gnk PLCB3 crystal structure of galphaq in complex with full-length human plcbeta3 4.0Å AUTH A.M.LYON,S.DUTTA,C.A.BOGUTH,G.SKINIOTIS,J.J.TESMERTITL FULL-LENGTH G ALPHA (Q)-PHOSPHOLIPASE C-BETA 3 STRUCTURETITL 2 REVEALS INTERFACES OF THE C-TERMINAL COILED-COIL DOMAIN.REF NAT.STRUCT.MOL.BIOL. V. 20 355 2013REFN ISSN 1545-9993PMID 23377541DOI 10.1038/NSMB.2497 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2fv8 RHOB the crystal structure of rhob in the gdp-bound state 1.9Å AUTH A.P.TURNBULL,M.SOUNDARARAJAN,C.SMEE,C.JOHANSSON,G.SCHOCH,AUTH 2 F.GORREC,J.BRAY,E.PAPAGRIGORIOU,F.VON DELFT,J.WEIGELT,AUTH 3 A.EDWARDS,C.ARROWSMITH,M.SUNDSTROM,D.DOYLETITL THE CRYSTAL STRUCTURE OF RHOB IN THE GDP-BOUND STATEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ery RRAS2 the crystal structure of the ras related protein rras2 (rras2) in the gdp bound state 1.7Å AUTH E.SALAH,G.SCHOCH,A.TURNBULL,E.PAPAGRIGORIOU,M.SOUNDARARAJAN,AUTH 2 N.BURGESS,J.ELKINS,C.GILEADI,O.GILEADI,F.VON DELFT,AUTH 3 A.EDWARDS,C.ARROWSMITH,J.WEIGELT,M.SUNDSTROM,D.DOYLETITL THE CRYSTAL STRUCTURE OF THE RAS RELATED PROTEIN RRAS2TITL 2 (RRAS2) IN THE GDP BOUND STATEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2fv8 RHOB the crystal structure of rhob in the gdp-bound state 1.9Å AUTH A.P.TURNBULL,M.SOUNDARARAJAN,C.SMEE,C.JOHANSSON,G.SCHOCH,AUTH 2 F.GORREC,J.BRAY,E.PAPAGRIGORIOU,F.VON DELFT,J.WEIGELT,AUTH 3 A.EDWARDS,C.ARROWSMITH,M.SUNDSTROM,D.DOYLETITL THE CRYSTAL STRUCTURE OF RHOB IN THE GDP-BOUND STATEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ery RRAS2 the crystal structure of the ras related protein rras2 (rras2) in the gdp bound state 1.7Å AUTH E.SALAH,G.SCHOCH,A.TURNBULL,E.PAPAGRIGORIOU,M.SOUNDARARAJAN,AUTH 2 N.BURGESS,J.ELKINS,C.GILEADI,O.GILEADI,F.VON DELFT,AUTH 3 A.EDWARDS,C.ARROWSMITH,J.WEIGELT,M.SUNDSTROM,D.DOYLETITL THE CRYSTAL STRUCTURE OF THE RAS RELATED PROTEIN RRAS2TITL 2 (RRAS2) IN THE GDP BOUND STATEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]