General Structure Information
| PDB ID | 2fv8 |
| HGNC Gene Label(s) | RHOB |
| Structure Name | the crystal structure of rhob in the gdp-bound state |
| Resolution | 1.9Å |
| Reference | AUTH A.P.TURNBULL,M.SOUNDARARAJAN,C.SMEE,C.JOHANSSON,G.SCHOCH,AUTH 2 F.GORREC,J.BRAY,E.PAPAGRIGORIOU,F.VON DELFT,J.WEIGELT,AUTH 3 A.EDWARDS,C.ARROWSMITH,M.SUNDSTROM,D.DOYLETITL THE CRYSTAL STRUCTURE OF RHOB IN THE GDP-BOUND STATEREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 175 |
| Number Of SNVs | 18 |
| Number Of Permutations | 8173 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.118 |
| p-value | 0.77 |
COSMIC
| Number Of Residues | 175 |
| Number Of SNVs | 4 |
| Number Of Permutations | 95 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.167 |
| p-value | 0.607 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 18 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.371 |
| p-value | 0.084 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
