Assessment of Structural Intolerance and Durability
General Structure Information 3F5N SERPINI1 structure of native human neuroserpin 3.15Å AUTH S.RICAGNO,S.CACCIA,G.SORRENTINO,G.ANTONINI,M.BOLOGNESITITL HUMAN NEUROSERPIN: STRUCTURE AND TIME-DEPENDENT INHIBITIONREF J.MOL.BIOL. V. 388 109 2009REFN ISSN 0022-2836PMID 19265707DOI 10.1016/J.JMB.2009.02.056 Variant Set Distributions Ripley’s K Analysis Plots
General Structure Information 3F5N SERPINI1 structure of native human neuroserpin 3.15Å AUTH S.RICAGNO,S.CACCIA,G.SORRENTINO,G.ANTONINI,M.BOLOGNESITITL HUMAN NEUROSERPIN: STRUCTURE AND TIME-DEPENDENT INHIBITIONREF J.MOL.BIOL. V. 388 109 2009REFN ISSN 0022-2836PMID 19265707DOI 10.1016/J.JMB.2009.02.056 Variant Set Distributions Ripley’s K Analysis Plots
General Structure Information 3F5N SERPINI1 structure of native human neuroserpin 3.15Å AUTH S.RICAGNO,S.CACCIA,G.SORRENTINO,G.ANTONINI,M.BOLOGNESITITL HUMAN NEUROSERPIN: STRUCTURE AND TIME-DEPENDENT INHIBITIONREF J.MOL.BIOL. V. 388 109 2009REFN ISSN 0022-2836PMID 19265707DOI 10.1016/J.JMB.2009.02.056 Variant Set Distributions Ripley’s K Analysis Plots
General Structure Information 3F5N SERPINI1 structure of native human neuroserpin 3.15Å AUTH S.RICAGNO,S.CACCIA,G.SORRENTINO,G.ANTONINI,M.BOLOGNESITITL HUMAN NEUROSERPIN: STRUCTURE AND TIME-DEPENDENT INHIBITIONREF J.MOL.BIOL. V. 388 109 2009REFN ISSN 0022-2836PMID 19265707DOI 10.1016/J.JMB.2009.02.056 Variant Set Distributions Ripley’s K Analysis Plots
General Structure Information 2zv6 SERPINB3 crystal structure of human squamous cell carcinoma antigen 1 2.7Å AUTH B.ZHENG,Y.MATOBA,T.KUMAGAI,C.KATAGIRI,T.HIBINO,AUTH 2 M.SUGIYAMATITL CRYSTAL STRUCTURE OF SCCA1 AND INSIGHT ABOUT THETITL 2 INTERACTION WITH JNK1REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 380 143 2009REFN ISSN 0006-291XPMID 19166818DOI 10.1016/J.BBRC.2009.01.057 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2jxd SPINK2 nmr structure of human serine protease inhibitor kazal type ii (spink2) -1.0Å AUTH T.CHEN,T.-R.LEE,W.-G.LIANG,W.-S.W.CHANG,P.-C.LYUTITL IDENTIFICATION OF TRYPSIN-INHIBITORY SITE ANDTITL 2 STRUCTURE DETERMINATION OF HUMAN SPINK2 SERINETITL 3 PROTEINASE INHIBITORREF PROTEINS V. 77 209 2009REFN ISSN 0887-3585PMID 19422058DOI 10.1002/PROT.22432 Variant Set Distributions Mapped Variants
General Structure Information 4dy0 SERPINE2 crystal structure of native protease nexin-1 with heparin 2.35Å AUTH W.LI,J.A.HUNTINGTONTITL CRYSTAL STRUCTURES OF PROTEASE NEXIN-1 IN COMPLEX WITHTITL 2 HEPARIN AND THROMBIN SUGGEST A 2-STEP RECOGNITION MECHANISM.REF BLOOD V. 120 459 2012REFN ISSN 0006-4971PMID 22618708DOI 10.1182/BLOOD-2012-03-415869 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2oay SERPING1 crystal structure of latent human c1-inhibitor 2.35Å AUTH L.BEINROHR,V.HARMAT,J.DOBO,Z.LORINCZ,P.GAL,P.ZAVODSZKYTITL C1 INHIBITOR SERPIN DOMAIN STRUCTURE REVEALS THE LIKELYTITL 2 MECHANISM OF HEPARIN POTENTIATION AND CONFORMATIONAL DISEASEREF J.BIOL.CHEM. V. 282 21100 2007REFN ISSN 0021-9258PMID 17488724DOI 10.1074/JBC.M700841200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3ut3 SERPINE1 a novel pai-i inhibitor and its structural mechanism 2.42Å AUTH Z.H.LIN,Z.B.HONG,X.L.SHI,L.H.HU,P.A.ANDREASEN,M.D.HUANGTITL A NOVEL PAI-I INHIBITOR AND ITS STRUCTURAL MECHANISMREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4acq A2M alpha-2 macroglobulin 4.3Å AUTH A.MARRERO,S.DUQUERROY,S.TRAPANI,T.GOULAS,T.GUEVARA,AUTH 2 G.R.ANDERSEN,J.NAVAZA,L.SOTTRUP-JENSEN,F.X.GOMIS-RUTHTITL THE CRYSTAL STRUCTURE OF HUMAN ALPHA(2)-MACROGLOBULINTITL 2 REVEALS A UNIQUE MOLECULAR CAGE.REF ANGEW.CHEM.INT.ED.ENGL. V. 51 3340 2012REFN ISSN 1433-7851PMID 22290936DOI 10.1002/ANIE.201108015 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants