Assessment of Structural Intolerance and Durability
General Structure Information 1a12 RCC1 regulator of chromosome condensation (rcc1) of human 1.7Å AUTH L.RENAULT,N.NASSAR,I.VETTER,J.BECKER,C.KLEBE,AUTH 2 M.ROTH,A.WITTINGHOFERTITL THE 1.7 A CRYSTAL STRUCTURE OF THE REGULATOR OFTITL 2 CHROMOSOME CONDENSATION (RCC1) REVEALS ATITL 3 SEVEN-BLADED PROPELLER.REF NATURE V. 392 97 1998REFN ISSN 0028-0836PMID 9510255DOI 10.1038/32204 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 3t06 ARHGEF11 crystal structure of the dh/ph fragment of pdzrhogef with n-terminal regulatory elements in complex with human rhoa 2.84Å AUTH J.A.BIELNICKI,A.V.SHKUMATOV,U.DEREWENDA,A.V.SOMLYO,AUTH 2 D.I.SVERGUN,Z.S.DEREWENDATITL INSIGHTS INTO THE MOLECULAR ACTIVATION MECHANISM OF THETITL 2 RHOA-SPECIFIC GUANINE NUCLEOTIDE EXCHANGE FACTOR, PDZRHOGEF.REF J.BIOL.CHEM. V. 286 35163 2011REFN ISSN 0021-9258PMID 21816819DOI 10.1074/JBC.M111.270918 Variant Set Distributions Ripley’s […]
General Structure Information 1htj ARHGEF11 structure of the rgs-like domain from pdz-rhogef 2.2Å AUTH K.L.LONGENECKER,M.E.LEWIS,H.CHIKUMI,J.S.GUTKIND,AUTH 2 Z.S.DEREWENDATITL STRUCTURE OF THE RGS-LIKE DOMAIN FROM PDZ-RHOGEF:TITL 2 LINKING HETEROTRIMERIC G PROTEIN-COUPLED SIGNALINGTITL 3 TO RHO GTPASES.REF STRUCTURE V. 9 559 2001REFN ISSN 0969-2126PMID 11470431DOI 10.1016/S0969-2126(01)00620-7 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]