General Structure Information 3fby COMP the crystal structure of the signature domain of cartilage oligomeric matrix protein. 3.15Å AUTH K.TAN,M.DUQUETTE,A.JOACHIMIAK,J.LAWLERTITL THE CRYSTAL STRUCTURE OF THE SIGNATURE DOMAIN OF CARTILAGETITL 2 OLIGOMERIC MATRIX PROTEIN: IMPLICATIONS FOR COLLAGEN,TITL 3 GLYCOSAMINOGLYCAN AND INTEGRIN BINDING.REF FASEB J. V. 23 2490 2009REFN ISSN 0892-6638PMID 19276170DOI 10.1096/FJ.08-128090 Variant Set Distributions Ripley’s […]
General Structure Information 3dem MASP1 cub1-egf-cub2 domain of human masp-1/3 2.3Å AUTH F.TEILLET,C.GABORIAUD,M.LACROIX,L.MARTIN,G.J.ARLAUD,AUTH 2 N.M.THIELENSTITL CRYSTAL STRUCTURE OF THE CUB1-EGF-CUB2 DOMAIN OF HUMANTITL 2 MASP-1/3 AND IDENTIFICATION OF ITS INTERACTION SITES WITHTITL 3 MANNAN-BINDING LECTIN AND FICOLINSREF J.BIOL.CHEM. V. 283 25715 2008REFN ISSN 0021-9258PMID 18596036DOI 10.1074/JBC.M803551200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2r2p EPHA5 kinase domain of human ephrin type-a receptor 5 (epha5) 2.4Å AUTH J.R.WALKER,D.CUERRIER,C.BUTLER-COLE,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 S.DHE-PAGANONTITL KINASE DOMAIN OF HUMAN EPHRIN TYPE-A RECEPTOR 5TITL 2 (EPHA5).REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3dwb ECE1 structure of human ece-1 complexed with phosphoramidon 2.38Å AUTH H.SCHULZ,G.E.DALE,Y.KARIMI-NEJAD,C.OEFNERTITL STRUCTURE OF HUMAN ENDOTHELIN-CONVERTING ENZYME I COMPLEXEDTITL 2 WITH PHOSPHORAMIDONREF J.MOL.BIOL. V. 385 178 2009REFN ISSN 0022-2836PMID 18992253DOI 10.1016/J.JMB.2008.10.052 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3evs GDF5 crystal structure of the gdf-5:bmp receptor ib complex. 2.1Å AUTH A.KOTZSCH,J.NICKEL,A.SEHER,W.SEBALD,T.D.MULLERTITL CRYSTAL STRUCTURE ANALYSIS REVEALS A SPRING-LOADED LATCH ASTITL 2 MOLECULAR MECHANISM FOR GDF-5-TYPE I RECEPTOR SPECIFICITY.REF EMBO J. V. 28 937 2009REFN ISSN 0261-4189PMID 19229295DOI 10.1038/EMBOJ.2009.37 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2x7o TGFBR1 crystal structure of tgfbri complexed with an indolinone inhibitor 3.7Å AUTH G.J.ROTH,A.HECKEL,T.BRANDL,M.GRAUERT,S.HOERER,J.T.KLEY,AUTH 2 G.SCHNAPP,P.BAUM,D.MENNERICH,A.SCHNAPP,J.E.PARKTITL DESIGN, SYNTHESIS AND EVALUATION OF INDOLINONES ASTITL 2 INHIBITORS OF THE TRANSFORMING GROWTH FACTOR BETA RECEPTORTITL 3 I (TGFBRI)REF J.MED.CHEM. V. 53 7287 2010REFN ISSN 0022-2623PMID 20919678DOI 10.1021/JM100812A Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 4fdj GALNS the molecular basis of mucopolysaccharidosis iv a, complex with galnac 2.81Å AUTH Y.RIVERA-COLON,E.K.SCHUTSKY,A.Z.KITA,S.C.GARMANTITL THE STRUCTURE OF HUMAN GALNS REVEALS THE MOLECULAR BASIS FORTITL 2 MUCOPOLYSACCHARIDOSIS IV A.REF J.MOL.BIOL. V. 423 736 2012REFN ISSN 0022-2836PMID 22940367DOI 10.1016/J.JMB.2012.08.020 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3c59 GLP1R crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain 2.3Å AUTH S.RUNGE,H.THOGERSEN,K.MADSEN,J.LAU,R.RUDOLPHTITL CRYSTAL STRUCTURE OF THE LIGAND-BOUND GLUCAGON-LIKETITL 2 PEPTIDE-1 RECEPTOR EXTRACELLULAR DOMAINREF J.BIOL.CHEM. V. 283 11340 2008REFN ISSN 0021-9258PMID 18287102DOI 10.1074/JBC.M708740200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2w86 FBN1 crystal structure of fibrillin-1 domains cbegf9hyb2cbegf10, calcium saturated form 1.8Å AUTH S.A.JENSEN,S.IQBAL,E.D.LOWE,C.REDFIELD,P.A.HANDFORDTITL STRUCTURE AND INTERDOMAIN INTERACTIONS OF A HYBRIDTITL 2 DOMAIN: A DISULPHIDE-RICH MODULE OF THETITL 3 FIBRILLIN/LTBP SUPERFAMILY OF MATRIX PROTEINS.REF STRUCTURE V. 17 759 2009REFN ISSN 0969-2126PMID 19446531DOI 10.1016/J.STR.2009.03.014 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3g81 SFTPD crystal structure of the trimeric neck and carbohydrate recognition domain of human surfactant protein d in complex with alpha methyl mannoside 1.8Å AUTH E.CROUCH,K.HARTSHORN,T.HORLACHER,B.MCDONALD,K.SMITH,AUTH 2 T.CAFARELLA,B.SEATON,P.H.SEEBERGER,J.HEADTITL RECOGNITION OF MANNOSYLATED LIGANDS AND INFLUENZA A VIRUS BYTITL 2 HUMAN SURFACTANT PROTEIN D: CONTRIBUTIONS OF AN EXTENDEDTITL 3 SITE AND RESIDUE 343.REF BIOCHEMISTRY […]