Assessment of Structural Intolerance and Durability
General Structure Information 4lnz MYO5B crystal structure of human myosin 5b globular domain 3.11Å AUTH H.VELVARSKA,D.NIESSINGTITL STRUCTURAL INSIGHTS INTO THE GLOBULAR TAILS OF THE HUMANTITL 2 TYPE V MYOSINS MYO5A, MYO5B, AND MYO5C.REF PLOS ONE V. 8 82065 2013REFN ESSN 1932-6203PMID 24339992DOI 10.1371/JOURNAL.PONE.0082065 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 1jlj GPHN 1.6 angstrom crystal structure of the human neuroreceptor anchoring and molybdenum cofactor biosynthesis protein gephyrin 1.6Å AUTH G.SCHWARZ,N.SCHRADER,R.R.MENDEL,H.J.HECHT,AUTH 2 H.SCHINDELINTITL CRYSTAL STRUCTURES OF HUMAN GEPHYRIN AND PLANTTITL 2 CNX1 G DOMAINS: COMPARATIVE ANALYSIS ANDTITL 3 FUNCTIONAL IMPLICATIONS.REF J.MOL.BIOL. V. 312 405 2001REFN ISSN 0022-2836PMID 11554796DOI 10.1006/JMBI.2001.4952 Variant Set Distributions Ripley’s […]
General Structure Information 4l8t MYO5C structure of the cargo binding domain from human myosin vc 2.95Å AUTH A.F.NASCIMENTO,D.M.TRINDADE,C.C.TONOLI,P.O.DE GIUSEPPE,AUTH 2 L.H.ASSIS,R.V.HONORATO,P.S.DE OLIVEIRA,P.MAHAJAN,AUTH 3 N.A.BURGESS-BROWN,F.VON DELFT,R.E.LARSON,M.T.MURAKAMITITL STRUCTURAL INSIGHTS INTO FUNCTIONAL OVERLAPPING ANDTITL 2 DIFFERENTIATION AMONG MYOSIN V MOTORS.REF J.BIOL.CHEM. V. 288 34131 2013REFN ISSN 0021-9258PMID 24097982DOI 10.1074/JBC.M113.507202 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 4dou ADIPOQ crystal structure of a single-chain trimer of human adiponectin globular domain 2.0Å AUTH X.MIN,B.LEMON,J.TANG,Q.LIU,R.ZHANG,N.WALKER,Y.LI,Z.WANGTITL CRYSTAL STRUCTURE OF A SINGLE-CHAIN TRIMER OF HUMANTITL 2 ADIPONECTIN GLOBULAR DOMAIN.REF FEBS LETT. V. 586 912 2012REFN ISSN 0014-5793PMID 22449980DOI 10.1016/J.FEBSLET.2012.02.024 Variant Set Distributions Mapped Variants
General Structure Information 2i6k IDI1 crystal structure of human type i ipp isomerase complexed with a substrate analog 2.0Å AUTH C.ZHANG,L.LIU,H.XU,Z.WEI,Y.WANG,Y.LIN,W.GONGTITL CRYSTAL STRUCTURES OF HUMAN IPP ISOMERASE: NEWTITL 2 INSIGHTS INTO THE CATALYTIC MECHANISMREF J.MOL.BIOL. V. 366 1437 2007REFN ISSN 0022-2836PMID 17137593DOI 10.1016/J.JMB.2006.10.092 Variant Set Distributions Mapped Variants
General Structure Information 3sea RHEB structure of rheb-y35a mutant in gdp- and gmppnp-bound forms 2.0Å AUTH M.T.MAZHAB-JAFARI,C.B.MARSHALL,N.ISHIYAMA,J.HO,V.DI PALMA,AUTH 2 V.STAMBOLIC,M.IKURATITL AN AUTOINHIBITED NONCANONICAL MECHANISM OF GTP HYDROLYSIS BYTITL 2 RHEB MAINTAINS MTORC1 HOMEOSTASIS.REF STRUCTURE V. 20 1528 2012REFN ISSN 0969-2126PMID 22819219DOI 10.1016/J.STR.2012.06.013 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]