Assessment of Structural Intolerance and Durability
General Structure Information 2cof AFAP1L2 solution structure of the c-terminal ph domain of hypothetical protein kiaa1914 from human -1.0Å AUTH H.LI,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL PH DOMAIN OFTITL 2 HYPOTHETICAL PROTEIN KIAA1914 FROM HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4lir NUP35 crystal structure of a nucleoporin 35kda (nup35) from homo sapiens at 2.46 a resolution 2.46Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGY (TCELL)TITL CRYSTAL STRUCTURE OF A NUCLEOPORIN 35KDA (NUP35) FROM HOMOTITL 2 SAPIENS AT 2.46 A RESOLUTIONREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 3u12 USP37 the pleckstrin homology (ph) domain of usp37 2.08Å AUTH A.DONG,U.B.NAIR,A.WERNIMONT,J.R.WALKER,J.WEIGELT,C.BOUNTRA,AUTH 2 A.M.EDWARDS,C.H.ARROWSMITH,S.DHE-PAGANON,AUTH 3 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE PLECKSTRIN HOMOLOGY (PH) DOMAIN OF USP37REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2cq4 RBM23 solution structure of rna binding domain in rna binding motif protein 23 -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN IN RNATITL 2 BINDING MOTIF PROTEIN 23REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1ujv MAGI2 solution structure of the second pdz domain of human membrane associated guanylate kinase inverted-2 (magi-2) -1.0Å AUTH N.NAMEKI,S.KOSHIBA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND PDZ DOMAIN OFTITL 2 HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASETITL 3 INVERTED-2 (MAGI-2)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3isu IQGAP3 crystal structure of the rgc domain of iqgap3 1.88Å AUTH L.NEDYALKOVA,W.TEMPEL,Y.TONG,L.CROMBET,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE RGC DOMAIN OF IQGAP3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dnz RBM23 solution structure of the second rna binding domain of rna binding motif protein 23 -1.0Å AUTH S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND RNA BINDINGTITL 2 DOMAIN OF RNA BINDING MOTIF PROTEIN 23REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2daz INADL solution structure of the 7th pdz domain of inad-like protein -1.0Å AUTH K.INOUE,T.NAGASHIMA,K.IZUMI,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 7TH PDZ DOMAIN OFTITL 2 INAD-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2diz TXNDC5 the solution structure of the third thioredoxin domain of human thioredoxin domain-containing protein 5 -1.0Å AUTH N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE THIRD THIOREDOXINTITL 2 DOMAIN OF HUMAN THIOREDOXIN DOMAIN-CONTAININGTITL 3 PROTEIN 5REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 2h00 METTL16 human methyltransferase 10 domain containing protein 2.0Å AUTH H.WU,J.MIN,H.ZENG,P.LOPPNAU,J.WEIGELT,M.SUNDSTROM,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF HUMAN METHYLTRANSFERASETITL 2 10 DOMAIN CONTAINING PROTEIN.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants