Assessment of Structural Intolerance and Durability
General Structure Information 2emp ZNF347 solution structure of the c2h2 type zinc finger (region 536- 568) of human zinc finger protein 347 -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 536-568) OF HUMAN ZINC FINGER PROTEIN 347REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2q9v MAGI1 crystal structure of the c890s mutant of the 4th pdz domain of human membrane associated guanylate kinase 2.0Å AUTH E.S.PILKA,V.HOZJAN,K.L.KAVANAGH,E.PAPAGRIGORIOU,C.COOPER,AUTH 2 J.M.ELKINS,D.A.DOYLE,F.VON DELFT,M.SUNDSTROM,C.A.ARROWSMITH,AUTH 3 J.WEIGELT,A.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE C890S MUTANT OF THE 4TH PDZ DOMAINTITL 2 OF HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASE.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 2p31 GPX7 crystal structure of human glutathione peroxidase 7 2.0Å AUTH K.L.KAVANAGH,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE PEROXIDASE 7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ene ZNF347 solution structure of the c2h2 type zinc finger (region 592- 624) of human zinc finger protein 347 -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 592-624) OF HUMAN ZINC FINGER PROTEIN 347REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3oln UHRF2 crystal structure of the sra domain of e3 ubiquitin-protein ligase uhrf2 2.3Å AUTH J.R.WALKER,S.XUE,G.V.AVVAKUMOV,C.BOUNTRA,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANON,AUTH 3 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE SET AND RING ASSOCIATED (SRA) DOMAIN OF HUMANTITL 2 UBIQUITIN-LIKE CONTAINING PHD AND RING FINGER DOMAINS 2TITL 3 (UHRF2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2h58 KIFC3 crystal structure of the kifc3 motor domain in complex with adp 1.85Å AUTH J.WANG,Y.SHEN,W.TEMPEL,R.LANDRY,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE KIFC3 MOTOR DOMAIN INTITL 2 COMPLEX WITH ADPREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yy0 MYCBP crystal structure of ms0802, c-myc-1 binding protein domain from homo sapiens 2.4Å AUTH Y.XIE,H.WANG,IHSANAWATI,S.KISHISHITA,C.TAKEMOTO,AUTH 2 K.MURAYAMA,M.SHIROZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF C-MYC-1 BINDING PROTEINTITL 2 DOMAIN FROM HOMO SAPIENSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dlk ZNF692 solution structure of the first and the second zf-c2h2 domains of zinc finger protein 692 -1.0Å AUTH H.P.ZHANG,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST AND THE SECONDTITL 2 ZF-C2H2 DOMAINS OF ZINC FINGER PROTEIN 692REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2db8 TRIM9 solution structures of the fn3 domain of human tripartite motif protein 9 -1.0Å AUTH M.SATO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE FN3 DOMAIN OF HUMANTITL 2 TRIPARTITE MOTIF PROTEIN 9REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3iv1 TSG101 coiled-coil domain of tumor susceptibility gene 101 2.5Å AUTH D.NECULAI,G.V.AVVAKUMOV,A.K.WERNIMONT,S.XUE,AUTH 2 J.R.WALKER,Y.LI,J.WEIGELT,C.BOUNTRA,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL COILED-COIL DOMAIN OF HUMAN TSG101REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants