Assessment of Structural Intolerance and Durability
General Structure Information 1wyn CNN2 solution structure of the ch domain of human calponin-2 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN OF HUMANTITL 2 CALPONIN-2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2djr ZBED2 solution structures of the c2h2 type zinc finger domain of human zinc finger bed domain containing protein 2 -1.0Å AUTH M.SATO,A.SASAGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE C2H2 TYPE ZINC FINGERTITL 2 DOMAIN OF HUMAN ZINC FINGER BED DOMAIN CONTAININGTITL 3 PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 2yu4 NSMCE2 solution structure of the sp-ring domain in non-smc element 2 homolog (mms21, s. cerevisiae) -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TARADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SP-RING DOMAIN INTITL 2 NON-SMC ELEMENT 2 HOMOLOG (MMS21, S. CEREVISIAE)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2nsq NEDD4L crystal structure of the c2 domain of the human e3 ubiquitin-protein ligase nedd4-like protein 1.85Å AUTH J.R.WALKER,G.V.AVVAKUMOV,S.XUE,C.BUTLER-COLE,AUTH 2 P.J.FINERTY JR.,J.WEIGELT,M.SUNDSTROM,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL THE C2 DOMAIN OF THE HUMAN E3 UBIQUITIN-PROTEIN LIGASETITL 2 NEDD4-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2yu8 ZNF347 solution structure of the c2h2 type zinc finger (region 648- 680) of human zinc finger protein 347 -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 648-680) OF HUMAN ZINC FINGER PROTEIN 347REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3edt KLC2 crystal structure of the mutated s328n hklc2 tpr domain 2.7Å AUTH H.ZHU,Y.SHEN,F.MACKENZIE,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF MUTATED S328N TPR DOMAIN OF HUMANTITL 2 KINESIN LIGHT CHAIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ctd ZNF512 solution structure of two zf-c2h2 domains from human zinc finger protein 512 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF TWO ZF-C2H2 DOMAINS FROMTITL 2 HUMAN ZINC FINGER PROTEIN 512REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wgo SORCS2 solution structure of the pkd domain from human vps10 domain-containing receptor sorcs2 -1.0Å AUTH E.CHIKAYAMA,T.KIGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PKD DOMAIN FROM HUMANTITL 2 VPS10 DOMAIN-CONTAINING RECEPTOR SORCS2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3rmu MCEE crystal structure of human methylmalonyl-coa epimerase, mcee 1.8Å AUTH A.CHAIKUAD,E.KRYSZTOFINSKA,D.S.FROESE,W.W.YUE,M.VOLLMAR,AUTH 2 J.R.C.MUNIZ,F.VON DELFT,J.WEIGELT,C.H.ARROWSMITH,AUTH 3 A.M.EDWARDS,C.BOUNTRA,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF HUMAN METHYLMALONYL-COA EPIMERASE, MCEEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3no8 BTBD2 crystal structure of the phr domain from human btbd2 protein 2.2Å AUTH P.SAMPATHKUMARTITL CRYSTAL STRUCTURE OF THE PHR DOMAIN FROM HUMAN BTBD2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants