Assessment of Structural Intolerance and Durability
General Structure Information 2dkz GAREM solution structure of the sam_pnt-domain of the hypothetical protein loc64762 -1.0Å AUTH A.K.GORONCY,M.SATO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SAM_PNT-DOMAIN OF THETITL 2 HYPOTHETICAL PROTEIN LOC64762REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dk6 PARP11 solution structure of wwe domain in poly (adp-ribose) polymerase family, member 11 (parp 11) -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF WWE DOMAIN IN POLYTITL 2 (ADP-RIBOSE) POLYMERASE FAMILY, MEMBER 11 (PARP 11)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ee0 PCDH9 solution structures of the ca domain of human protocadherin 9 -1.0Å AUTH M.SATO,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURES OF THE CA DOMAIN OF HUMANTITL 2 PROTOCADHERIN 9REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dah UBQLN3 solution structure of the c-terminal uba domain in the human ubiquilin 3 -1.0Å AUTH C.ZHAO,T.KIGAWA,M.SATO,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL UBA DOMAIN INTITL 2 THE HUMAN UBIQUILIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ed0 ABI2 solution structure of the sh3 domain of abl interactor 2 (abelson interactor 2) -1.0Å AUTH H.ABE,N.TOCHIO,K.MIYAMOTO,K.SAITO,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF ABLTITL 2 INTERACTOR 2 (ABELSON INTERACTOR 2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ihx PRDM10 methyltransferase domain of human pr domain-containing protein 10 2.5Å AUTH M.F.AMAYA,L.DOMBROVSKI,S.NI,C.BOUNTRA,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOTCHKAREV,J.MIN,A.N.PLOTNIKOV,AUTH 3 H.WU,STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL METHYLTRANSFERASE DOMAIN OF HUMAN PR DOMAIN-CONTAININGTITL 2 PROTEIN 10REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2cpd A1CF solution structure of the rna recognition motif of human apobec-1 complementation factor, acf -1.0Å AUTH T.NAGATA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA RECOGNITION MOTIF OFTITL 2 HUMAN APOBEC-1 COMPLEMENTATION FACTOR, ACFREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wel RBM12 solution structure of rna binding domain in np_006038 -1.0Å AUTH T.SOMEYA,Y.MUTO,T.NAGATA,S.SUZUKI,M.INOUE,T.KIGAWA,AUTH 2 T.TERADA,M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 NP_006038REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3n50 EBF3 human early b-cell factor 3 (ebf3) ipt/tig and hlhlh domains 3.1Å AUTH M.I.SIPONEN,M.WISNIEWSKA,L.LEHTIO,I.JOHANSSON,L.SVENSSON,AUTH 2 G.RASZEWSKI,L.NILSSON,M.SIGVARDSSON,H.BERGLUNDTITL STRUCTURAL DETERMINATION OF FUNCTIONAL DOMAINS IN EARLYTITL 2 B-CELL FACTOR (EBF) FAMILY OF TRANSCRIPTION FACTORS REVEALSTITL 3 SIMILARITIES TO REL DNA-BINDING PROTEINS AND A NOVELTITL 4 DIMERIZATION MOTIF.REF J.BIOL.CHEM. V. 285 25875 2010REFN ISSN 0021-9258PMID […]
General Structure Information 3ihl CTPS2 human ctps2 crystal structure 2.8Å AUTH M.MOCHE,M.I.SIPONEN,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,T.KARLBERG,AUTH 4 T.KOTENYOVA,A.KOTZSCH,T.KRAGH NIELSEN,T.NYMAN,C.PERSSON,AUTH 5 A.K.ROOS,J.SAGEMARK,H.SCHUELER,P.SCHUTZ,A.G.THORSELL,AUTH 6 L.TRESAUGUES,S.VAN DEN BERG,J.WEIGELT,M.WELIN,M.WISNIEWSKA,AUTH 7 P.NORDLUNDTITL HUMAN CTPS2 CRYSTAL STRUCTUREREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants