Assessment of Structural Intolerance and Durability
General Structure Information 2l08 UPF3A solution nmr structure of nonsense mrna reducing factor 3a from h. sapiens, northeast structural genomics consortium target hr4714b -1.0Å AUTH R.MANI,L.MAO,C.CICCOSANTI,R.SHASTRY,T.B.ACTON,R.XIAO,AUTH 2 G.V.T.SWAPNA,J.K.EVERETT,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF NONSENSE MRNA REDUCING FACTOR 3ATITL 2 FROM H. SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUMTITL 3 TARGET HR4714BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 4iej DMAP1 crystal structure of a dna methyltransferase 1 associated protein 1 (dmap1) from homo sapiens at 1.45 a resolution 1.45Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGYTITL CRYSTAL STRUCTURE OF A DNA METHYLTRANSFERASE 1 ASSOCIATEDTITL 2 PROTEIN 1 (DMAP1) FROM HOMO SAPIENS AT 1.45 A RESOLUTIONREF […]
General Structure Information 3q2e BRWD1 crystal structure of the second bromodomain of human bromodomain and wd repeat-containing protein 1 isoform a (wdr9) 1.74Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,M.MANGOS,T.KEATES,J.P.LAMBERT,AUTH 2 D.BARSYTE-LOVEJOY,I.FELLETAR,R.VOLKMER,S.MULLER,T.PAWSON,AUTH 3 A.C.GINGRAS,C.H.ARROWSMITH,S.KNAPPTITL HISTONE RECOGNITION AND LARGE-SCALE STRUCTURAL ANALYSIS OFTITL 2 THE HUMAN BROMODOMAIN FAMILY.REF CELL(CAMBRIDGE,MASS.) V. 149 214 2012REFN ISSN 0092-8674PMID 22464331DOI 10.1016/J.CELL.2012.02.013 Variant Set Distributions Mapped Variants
General Structure Information 2ht9 GLRX2 the structure of dimeric human glutaredoxin 2 1.9Å AUTH C.JOHANSSON,K.L.KAVANAGH,O.GILEADI,U.OPPERMANNTITL REVERSIBLE SEQUESTRATION OF ACTIVE SITE CYSTEINES IN ATITL 2 2FE-2S-BRIDGED DIMER PROVIDES A MECHANISM FOR GLUTAREDOXIN 2TITL 3 REGULATION IN HUMAN MITOCHONDRIAREF J.BIOL.CHEM. V. 282 3077 2007REFN ISSN 0021-9258PMID 17121859DOI 10.1074/JBC.M608179200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 1x5w ZFP64 solution structure of the c2h2 type zinc-binding domain of human zinc finger protein 64, isoforms 1 and 2 -1.0Å AUTH M.YONEYAMA,S.KOSHIBA,N.TOCHIO,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC-BINDINGTITL 2 DOMAIN OF HUMAN ZINC FINGER PROTEIN 64, ISOFORMS 1TITL 3 AND 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s […]
General Structure Information 2dmd ZFP64 solution structure of the n-terminal c2h2 type zinc-binding domain of the zinc finger protein 64, isoforms 1 and 2 -1.0Å AUTH M.YONEYAMA,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINAL C2H2 TYPETITL 2 ZINC-BINDING DOMAIN OF THE ZINC FINGER PROTEIN 64,TITL 3 ISOFORMS 1 AND 2REF TO BE PUBLISHEDREFN Variant Set […]
General Structure Information 2eqx KBTBD4 solution structure of the back domain of kelch repeat and btb domain-containing protein 4 -1.0Å AUTH M.IMAI,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE BACK DOMAIN OF KELCHTITL 2 REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wvo NANS solution structure of rsgi ruh-029, an antifreeze protein like domain in human n-acetylneuraminic acid phosphate synthase gene. -1.0Å AUTH T.HAMADA,Y.ITO,T.ABE,F.HAYASHI,P.GUNTERT,M.INOUE,AUTH 2 T.KIGAWA,T.TERADA,M.SHIROUZU,M.YOSHIDA,A.TANAKA,AUTH 3 S.SUGANO,S.YOKOYAMA,H.HIROTATITL SOLUTION STRUCTURE OF THE ANTIFREEZE-LIKE DOMAINTITL 2 OF HUMAN SIALIC ACID SYNTHASEREF PROTEIN SCI. V. 15 1010 2006REFN ISSN 0961-8368PMID 16597820DOI 10.1110/PS.051700406 Variant Set Distributions Mapped […]
General Structure Information 1x4w ZFAND3 solution structure of the zf-an1 domain from human hypothetical protein flj13222 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-AN1 DOMAIN FROM HUMANTITL 2 HYPOTHETICAL PROTEIN FLJ13222REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3dcy C12orf5 crystal structure a tp53-induced glycolysis and apoptosis regulator protein from homo sapiens. 1.75Å AUTH J.G.MCCOY,C.A.BINGMAN,G.E.WESENBERG,AUTH 2 G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE A TP53-INDUCED GLYCOLYSIS ANDTITL 2 APOPTOSIS REGULATOR PROTEIN FROM HOMO SAPIENS.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants