Assessment of Structural Intolerance and Durability
General Structure Information 2ct6 SH3BGRL2 solution structure of the sh3 domain-binding glutamic acid- rich-like protein 2 -1.0Å AUTH K.MIYAMOTO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN-BINDINGTITL 2 GLUTAMIC ACID-RICH-LIKE PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1v5j IGSF9 solution structure of rsgi ruh-008, fn3 domain in human cdna -1.0Å AUTH Y.DOI-KATAYAMA,F.HAYASHI,H.HIROTA,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-008, A FN3 DOMAINTITL 2 IN HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3gf9 ITSN2 crystal structure of human intersectin 2 rhogef domain 2.5Å AUTH Y.SHEN,Y.TONG,W.TEMPEL,Y.LI,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN INTERSECTIN 2 RHOGEFTITL 2 DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1zq9 DIMT1 crystal structure of human dimethyladenosine transferase 1.9Å AUTH H.WU,A.DONG,H.ZENG,P.LOPPNAU,M.SUNDSTROM,AUTH 2 C.ARROWSMITH,A.EDWARDS,A.BOCHKAREV,A.PLOTNIKOVTITL CRYSTAL STRUCTURE OF HUMAN DIMETHYLADENOSINETITL 2 TRANSFERASE WITH SAMREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3nar ZHX1 crystal structure of zhx1 hd4 (zinc-fingers and homeoboxes protein 1, homeodomain 4) 2.6Å AUTH L.E.BIRD,J.REN,J.E.NETTLESHIP,G.E.FOLKERS,R.J.OWENS,AUTH 2 D.K.STAMMERSTITL NOVEL STRUCTURAL FEATURES IN TWO ZHX HOMEODOMAINS DERIVEDTITL 2 FROM A SYSTEMATIC STUDY OF SINGLE AND MULTIPLE DOMAINSREF BMC STRUCT.BIOL. V. 10 13 2010REFN ESSN 1472-6807PMID 20509910DOI 10.1186/1472-6807-10-13 Variant Set Distributions Mapped Variants
General Structure Information 3db5 PRDM4 crystal structure of methyltransferase domain of human pr domain- containing protein 4 2.15Å AUTH H.ZENG,M.F.AMAYA,P.LOPPNAU,A.BOCHKAREV,J.MIN,A.N.PLOTNIKOV,AUTH 2 H.WUTITL THE CRYSTAL STRUCTURE OF METHYLTRANSFERASE DOMAIN OF HUMANTITL 2 PR DOMAIN-CONTAINING PROTEIN 4.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1ue9 ITSN2 solution structure of the fourth sh3 domain of human intersectin 2 (kiaa1256) -1.0Å AUTH N.TOCHIO,T.KIGAWA,S.KOSHIBA,N.KOBAYASHI,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FOURTH SH3 DOMAIN OFTITL 2 HUMAN INTERSECTIN 2 (KIAA1256)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dhz RAPGEFL1 solution structure of the ra domain in the human link guanine nucleotide exchange factor ii (link-gefii) -1.0Å AUTH C.ZHAO,T.KIGAWA,M.YONEYAMA,S.KOSHIBA,T.HARADA,AUTH 2 S.WATANABE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RA DOMAIN IN THE HUMANTITL 2 LINK GUANINE NUCLEOTIDE EXCHANGE FACTOR IITITL 3 (LINK-GEFII)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2qq8 TBC1D14 crystal structure of the putative rabgap domain of human tbc1 domain family member 14 2.0Å AUTH Y.TONG,W.TEMPEL,S.DIMOV,R.LANDRY,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE PUTATIVE RABGAP DOMAIN OFTITL 2 HUMAN TBC1 DOMAIN FAMILY MEMBER 14.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 1wiz SATB2 solution structure of the first cut domain of kiaa1034 protein -1.0Å AUTH K.INOUE,S.NAMEKI,F.HAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST CUT DOMAIN OFTITL 2 KIAA1034 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants