Assessment of Structural Intolerance and Durability
General Structure Information 2yqp DDX59 solution structure of the zf-hit domain in dead (asp-glu- ala-asp) box polypeptide 59 -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TARADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-HIT DOMAIN IN DEADTITL 2 (ASP-GLU-ALA-ASP) BOX POLYPEPTIDE 59REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2jng CUL7 solution structure of the cul7-cph domain from homo sapiens; northeast structural genomics consortium target ht1. -1.0Å AUTH L.KAUSTOV,J.LUKIN,A.LEMAK,S.DUAN,M.HO,R.DOHERTY,AUTH 2 L.Z.PENN,C.H.ARROWSMITHTITL THE CONSERVED CPH DOMAINS OF CUL7 AND PARC ARETITL 2 PROTEIN-PROTEIN INTERACTION MODULES THAT BIND THETITL 3 TETRAMERIZATION DOMAIN OF P53REF J.BIOL.CHEM. V. 282 11300 2007REFN ISSN 0021-9258PMID 17298945DOI 10.1074/JBC.M611297200 […]
General Structure Information 1a02 NFATC2 structure of the dna binding domains of nfat, fos and jun bound to dna 2.7Å AUTH L.CHEN,J.N.GLOVER,P.G.HOGAN,A.RAO,S.C.HARRISONTITL STRUCTURE OF THE DNA-BINDING DOMAINS FROM NFAT,TITL 2 FOS AND JUN BOUND SPECIFICALLY TO DNA.REF NATURE V. 392 42 1998REFN ISSN 0028-0836PMID 9510247DOI 10.1038/32100 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2cpn TARBP2 solution structure of the second dsrbd of tar rna-binding protein 2 -1.0Å AUTH T.NAGATA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND DSRBD OF TARTITL 2 RNA-BINDING PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2oo1 BRD3 crystal structure of the bromo domain 2 of human bromodomain containing protein 3 (brd3) 1.7Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,M.MANGOS,T.KEATES,J.P.LAMBERT,AUTH 2 D.BARSYTE-LOVEJOY,I.FELLETAR,R.VOLKMER,S.MULLER,T.PAWSON,AUTH 3 A.C.GINGRAS,C.H.ARROWSMITH,S.KNAPPTITL HISTONE RECOGNITION AND LARGE-SCALE STRUCTURAL ANALYSIS OFTITL 2 THE HUMAN BROMODOMAIN FAMILY.REF CELL(CAMBRIDGE,MASS.) V. 149 214 2012REFN ISSN 0092-8674PMID 22464331DOI 10.1016/J.CELL.2012.02.013 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3q0n PUM1 crystal structure of the pumilio-homology domain from human pumilio1 in complex with erk2 nre 2.4Å AUTH G.LU,T.M.HALLTITL ALTERNATE MODES OF COGNATE RNA RECOGNITION BY HUMAN PUMILIOTITL 2 PROTEINS.REF STRUCTURE V. 19 361 2011REFN ISSN 0969-2126PMID 21397187DOI 10.1016/J.STR.2010.12.019 Variant Set Distributions Mapped Variants
General Structure Information 3q0n PUM1 crystal structure of the pumilio-homology domain from human pumilio1 in complex with erk2 nre 2.4Å AUTH G.LU,T.M.HALLTITL ALTERNATE MODES OF COGNATE RNA RECOGNITION BY HUMAN PUMILIOTITL 2 PROTEINS.REF STRUCTURE V. 19 361 2011REFN ISSN 0969-2126PMID 21397187DOI 10.1016/J.STR.2010.12.019 Variant Set Distributions Mapped Variants
General Structure Information 3q0n PUM1 crystal structure of the pumilio-homology domain from human pumilio1 in complex with erk2 nre 2.4Å AUTH G.LU,T.M.HALLTITL ALTERNATE MODES OF COGNATE RNA RECOGNITION BY HUMAN PUMILIOTITL 2 PROTEINS.REF STRUCTURE V. 19 361 2011REFN ISSN 0969-2126PMID 21397187DOI 10.1016/J.STR.2010.12.019 Variant Set Distributions Mapped Variants
General Structure Information 3qu6 IRF3 crystal structure of irf-3 dbd free form 2.3Å AUTH P.DE IOANNES,C.R.ESCALANTE,A.K.AGGARWALTITL STRUCTURES OF APO IRF-3 AND IRF-7 DNA BINDING DOMAINS:TITL 2 EFFECT OF LOOP L1 ON DNA BINDING.REF NUCLEIC ACIDS RES. V. 39 7300 2011REFN ISSN 0305-1048PMID 21596780DOI 10.1093/NAR/GKR325 Variant Set Distributions Mapped Variants
General Structure Information 3qu6 IRF3 crystal structure of irf-3 dbd free form 2.3Å AUTH P.DE IOANNES,C.R.ESCALANTE,A.K.AGGARWALTITL STRUCTURES OF APO IRF-3 AND IRF-7 DNA BINDING DOMAINS:TITL 2 EFFECT OF LOOP L1 ON DNA BINDING.REF NUCLEIC ACIDS RES. V. 39 7300 2011REFN ISSN 0305-1048PMID 21596780DOI 10.1093/NAR/GKR325 Variant Set Distributions Mapped Variants