Assessment of Structural Intolerance and Durability
General Structure Information 2db8 TRIM9 solution structures of the fn3 domain of human tripartite motif protein 9 -1.0Å AUTH M.SATO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE FN3 DOMAIN OF HUMANTITL 2 TRIPARTITE MOTIF PROTEIN 9REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2yrg TRIM5 solution structure of the b-box domain from tripartite motif-containing protein 5 -1.0Å AUTH X.R.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE B-BOX DOMAIN FROMTITL 2 TRIPARTITE MOTIF-CONTAINING PROTEIN 5REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yqm RUFY1 solution structure of the fyve domain in zinc finger fyve domain-containing protein 12 -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FYVE DOMAIN IN ZINCTITL 2 FINGER FYVE DOMAIN-CONTAINING PROTEIN 12REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wy8 UHRF2 solution structure of the n-terminal ubiquitin-like domain in human np95/icbp90-like ring finger protein (nirf) -1.0Å AUTH C.ZHAO,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINALTITL 2 UBIQUITIN-LIKE DOMAIN IN HUMAN NP95/ICBP90-LIKETITL 3 RING FINGER PROTEIN (NIRF)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1r8u CITED2 nmr structure of cbp taz1/cited2 complex -1.0Å AUTH R.N.DE GUZMAN,M.A.MARTINEZ-YAMOUT,H.J.DYSON,AUTH 2 P.E.WRIGHTTITL INTERACTION OF THE TAZ1 DOMAIN OF THE CREB-BINDINGTITL 2 PROTEIN WITH THE ACTIVATION DOMAIN OF CITED2:TITL 3 REGULATION BY COMPETITION BETWEEN INTRINSICALLYTITL 4 UNSTRUCTURED LIGANDS FOR NON-IDENTICAL BINDINGTITL 5 SITES.REF J.BIOL.CHEM. V. 279 3042 2004REFN ISSN 0021-9258PMID 14594809DOI […]
General Structure Information 1jm7 BARD1 solution structure of the brca1/bard1 ring-domain heterodimer -1.0Å AUTH P.S.BRZOVIC,P.RAJAGOPAL,D.W.HOYT,M.C.KING,AUTH 2 R.E.KLEVITTITL STRUCTURE OF A BRCA1-BARD1 HETERODIMERIC RING-RINGTITL 2 COMPLEX.REF NAT.STRUCT.BIOL. V. 8 833 2001REFN ISSN 1072-8368PMID 11573085DOI 10.1038/NSB1001-833 Variant Set Distributions Mapped Variants
General Structure Information 4llb KAT6A crystal structure of moz double phd finger histone h3k14ac complex 2.5Å AUTH I.DREVENY,S.E.DEEVES,J.FULTON,B.YUE,M.MESSMER,AUTH 2 A.BHATTACHARYA,H.M.COLLINS,D.M.HEERYTITL THE DOUBLE PHD FINGER DOMAIN OF MOZ/MYST3 INDUCESTITL 2 ALPHA-HELICAL STRUCTURE OF THE HISTONE H3 TAIL TO FACILITATETITL 3 ACETYLATION AND METHYLATION SAMPLING AND MODIFICATION.REF NUCLEIC ACIDS RES. V. 42 822 2014REFN ISSN 0305-1048PMID 24150941DOI […]
General Structure Information 2kg5 ARAP3 nmr solution structure of arap3-sam -1.0Å AUTH M.LEONE,J.CELLITTI,M.PELLECCHIATITL THE SAM DOMAIN OF THE LIPID PHOSPHATASE SHIP2TITL 2 ADOPTS A COMMON MODEL TO INTERACT WITH ARAP3-SAMTITL 3 AND EPHA2-SAM.REF BMC STRUCT.BIOL. V. 9 59 2009REFN ESSN 1472-6807PMID 19765305DOI 10.1186/1472-6807-9-59 Variant Set Distributions Mapped Variants
General Structure Information 1tdh NEIL1 crystal structure of human endonuclease viii-like 1 (neil1) 2.1Å AUTH S.DOUBLIE,V.BANDARU,J.P.BOND,S.S.WALLACETITL THE CRYSTAL STRUCTURE OF HUMAN ENDONUCLEASETITL 2 VIII-LIKE 1 (NEIL1) REVEALS A ZINCLESS FINGERTITL 3 MOTIF REQUIRED FOR GLYCOSYLASE ACTIVITY.REF PROC.NATL.ACAD.SCI.USA V. 101 10284 2004REFN ISSN 0027-8424PMID 15232006DOI 10.1073/PNAS.0402051101 Variant Set Distributions Mapped Variants
General Structure Information 1x6f ZNF462 solution structures of the c2h2 type zinc finger domain of human zinc finger protein 462 -1.0Å AUTH M.SATO,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURES OF THE C2H2 TYPE ZINC FINGERTITL 2 DOMAIN OF HUMAN ZINC FINGER PROTEIN 462REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants