Assessment of Structural Intolerance and Durability
General Structure Information 2l80 USP13 solution structure of the zinc finger domain of usp13 -1.0Å AUTH Y.ZHANG,A.SONG,C.ZHOU,Z.ZHOU,H.HUTITL BIOCHEMICAL CHARACTERIZATION OF THE UBIQUITIN RECEPTORS INTITL 2 USP13 REVEALS DIFFERENT CATALYTIC ACTIVATION OFTITL 3 DEUBIQUITINATION FROM ITS ANALOGUE USP5REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4ljq RNF31 crystal structure of the catalytic core of e3 ligase hoip 2.45Å AUTH B.STIEGLITZ,R.R.RANA,M.G.KOLIOPOULOS,A.C.MORRIS-DAVIES,AUTH 2 V.SCHAEFFER,E.CHRISTODOULOU,S.HOWELL,N.R.BROWN,I.DIKIC,AUTH 3 K.RITTINGERTITL STRUCTURAL BASIS FOR LIGASE-SPECIFIC CONJUGATION OF LINEARTITL 2 UBIQUITIN CHAINS BY HOIP.REF NATURE V. 503 422 2013REFN ISSN 0028-0836PMID 24141947DOI 10.1038/NATURE12638 Variant Set Distributions Mapped Variants
General Structure Information 3fdw SYTL4 crystal structure of a c2 domain from human synaptotagmin- like protein 4 2.2Å AUTH J.B.BONANNO,M.RUTTER,K.T.BAIN,S.MILLER,R.ROMERO,AUTH 2 S.WASSERMAN,J.M.SAUDER,S.K.BURLEY,S.C.ALMOTITL CRYSTAL STRUCTURE OF A C2 DOMAIN FROM HUMANTITL 2 SYNAPTOTAGMIN-LIKE PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ct7 RNF31 solution structure of the ibr domain of the ring finger protein 31 protein -1.0Å AUTH K.MIYAMOTO,S.KOSHIBA,T.TOMIZAWA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE IBR DOMAIN OF THE RINGTITL 2 FINGER PROTEIN 31 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ecn RNF141 solution structure of the ring domain of the human ring finger protein 141 -1.0Å AUTH K.MIYAMOTO,N.TOCHIO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RING DOMAIN OF THE HUMANTITL 2 RING FINGER PROTEIN 141REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ctt DNAJA3 solution structure of zinc finger domain from human dnaj subfamily a menber 3 -1.0Å AUTH N.KOBAYASHI,N.TOCHIO,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF ZINC FINGER DOMAIN FROMTITL 2 HUMAN DNAJ SUBFAMILY A MENBER 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3fkc ZBTB33 crystal structure of human zinc finger and btb domain containing 33 1.7Å AUTH P.FILIPPAKOPOULOS,A.BULLOCK,T.KEATES,N.BURGESS-BROWN,AUTH 2 J.MUNIZ,F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,AUTH 3 C.BOUNTRA,S.KNAPPTITL CRYSTAL STRUCTURE OF HUMAN ZINC FINGER AND BTB DOMAINTITL 2 CONTAINING 33REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yrh ZNF473 solution structure of the c2h2-type zinc finger domain (699- 729) from zinc finger protein 473 -1.0Å AUTH X.R.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2-TYPE ZINC FINGERTITL 2 DOMAIN (699-729) FROM ZINC FINGER PROTEIN 473REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4i7c SIAH1 siah1 mutant bound to synthetic peptide (ace)klrpv(23p)mvrpwvr 2.8Å AUTH J.L.STEBBINS,E.SANTELLI,Y.FENG,S.K.DE,A.PURVES,AUTH 2 K.MOTAMEDCHABOKI,B.WU,Z.A.RONAI,R.C.LIDDINGTON,M.PELLECCHIATITL STRUCTURE-BASED DESIGN OF COVALENT SIAH INHIBITORS.REF CHEM.BIOL. V. 20 973 2013REFN ISSN 1074-5521PMID 23891150DOI 10.1016/J.CHEMBIOL.2013.06.008 Variant Set Distributions Mapped Variants
General Structure Information 4nn2 PHF6 protein crystal structure of human borjeson-forssman-lehmann syndrome associated protein phf6 1.47Å AUTH Z.LIU,F.LI,J.ZHANG,Y.MEI,J.WU,Y.SHITITL CRYSTAL STRUCTURE OF THE SECOND EXTENDED PHD DOMAIN OF HUMANTITL 2 PHF6 PROTEINREF J.BIOL.CHEM. 2014REFN ESSN 1083-351X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants