Assessment of Structural Intolerance and Durability
General Structure Information 1xdv SOS1 experimentally phased structure of human the son of sevenless protein at 4.1 ang. 4.1Å AUTH H.SONDERMANN,S.M.SOISSON,S.BOYKEVISCH,S.S.YANG,AUTH 2 D.BAR-SAGI,J.KURIYANTITL STRUCTURAL ANALYSIS OF AUTOINHIBITION IN THE RASTITL 2 ACTIVATOR SON OF SEVENLESS.REF CELL(CAMBRIDGE,MASS.) V. 119 393 2004REFN ISSN 0092-8674PMID 15507210DOI 10.1016/J.CELL.2004.10.005 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 3jui EIF2B5 crystal structure of the c-terminal domain of human translation initiation factor eif2b epsilon subunit 2.0Å AUTH J.WEI,H.XU,C.ZHANG,M.WANG,F.GAO,W.GONGTITL CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMANTITL 2 TRANSLATION INITIATION FACTOR EIF2B EPSILON SUBUNITREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4li0 RAB8A crystal structure of gdp-bound rab8:grab 3.3Å AUTH Z.GUO,X.HOU,R.S.GOODY,A.ITZENTITL INTERMEDIATES IN THE GUANINE NUCLEOTIDE EXCHANGE REACTION OFTITL 2 RAB8 PROTEIN CATALYZED BY GUANINE NUCLEOTIDE EXCHANGETITL 3 FACTORS RABIN8 AND GRAB.REF J.BIOL.CHEM. V. 288 32466 2013REFN ISSN 0021-9258PMID 24072714DOI 10.1074/JBC.M113.498329 Variant Set Distributions Mapped Variants
General Structure Information 1xdv SOS1 experimentally phased structure of human the son of sevenless protein at 4.1 ang. 4.1Å AUTH H.SONDERMANN,S.M.SOISSON,S.BOYKEVISCH,S.S.YANG,AUTH 2 D.BAR-SAGI,J.KURIYANTITL STRUCTURAL ANALYSIS OF AUTOINHIBITION IN THE RASTITL 2 ACTIVATOR SON OF SEVENLESS.REF CELL(CAMBRIDGE,MASS.) V. 119 393 2004REFN ISSN 0092-8674PMID 15507210DOI 10.1016/J.CELL.2004.10.005 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 3jui EIF2B5 crystal structure of the c-terminal domain of human translation initiation factor eif2b epsilon subunit 2.0Å AUTH J.WEI,H.XU,C.ZHANG,M.WANG,F.GAO,W.GONGTITL CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMANTITL 2 TRANSLATION INITIATION FACTOR EIF2B EPSILON SUBUNITREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4li0 RAB8A crystal structure of gdp-bound rab8:grab 3.3Å AUTH Z.GUO,X.HOU,R.S.GOODY,A.ITZENTITL INTERMEDIATES IN THE GUANINE NUCLEOTIDE EXCHANGE REACTION OFTITL 2 RAB8 PROTEIN CATALYZED BY GUANINE NUCLEOTIDE EXCHANGETITL 3 FACTORS RABIN8 AND GRAB.REF J.BIOL.CHEM. V. 288 32466 2013REFN ISSN 0021-9258PMID 24072714DOI 10.1074/JBC.M113.498329 Variant Set Distributions Mapped Variants
General Structure Information 1foe RAC1 crystal structure of rac1 in complex with the guanine nucleotide exchange region of tiam1 2.8Å AUTH D.K.WORTHYLAKE,K.L.ROSSMAN,J.SONDEKTITL CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THETITL 2 GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1.REF NATURE V. 408 682 2000REFN ISSN 0028-0836PMID 11130063DOI 10.1038/35047014 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3t6g BCAR1 structure of the complex between nsp3 (shep1) and p130cas 2.5Å AUTH P.D.MACE,Y.WALLEZ,M.K.DOBACZEWSKA,J.J.LEE,H.ROBINSON,AUTH 2 E.B.PASQUALE,S.J.RIEDLTITL NSP-CAS PROTEIN STRUCTURES REVEAL A PROMISCUOUS INTERACTIONTITL 2 MODULE IN CELL SIGNALING.REF NAT.STRUCT.MOL.BIOL. V. 18 1381 2011REFN ISSN 1545-9993PMID 22081014DOI 10.1038/NSMB.2152 Variant Set Distributions Mapped Variants
General Structure Information 2dm1 VAV2 solution structure of the second sh3 domain of human protein vav-2 -1.0Å AUTH H.ENDO,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND SH3 DOMAIN OFTITL 2 HUMAN PROTEIN VAV-2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2fu5 RABIF structure of rab8 in complex with mss4 2.0Å AUTH A.ITZEN,O.PYLYPENKO,R.S.GOODY,K.ALEXANDROV,A.RAKTITL NUCLEOTIDE EXCHANGE VIA LOCAL PROTEINTITL 2 UNFOLDING-STRUCTURE OF RAB8 IN COMPLEX WITH MSS4REF EMBO J. V. 25 1445 2006REFN ISSN 0261-4189PMID 16541104DOI 10.1038/SJ.EMBOJ.7601044 Variant Set Distributions Mapped Variants