Assessment of Structural Intolerance and Durability
General Structure Information 1wgm UBE4A solution structure of the u-box in human ubiquitin conjugation factor e4a -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE U-BOX IN HUMAN UBIQUITINTITL 2 CONJUGATION FACTOR E4AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wgm UBE4A solution structure of the u-box in human ubiquitin conjugation factor e4a -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE U-BOX IN HUMAN UBIQUITINTITL 2 CONJUGATION FACTOR E4AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1q7l ACY1 zn-binding domain of the t347g mutant of human aminoacylase- i 1.4Å AUTH H.A.LINDNER,V.V.LUNIN,A.ALARY,R.HECKER,M.CYGLER,AUTH 2 R.MENARDTITL ESSENTIAL ROLES OF ZINC LIGATION AND ENZYMETITL 2 DIMERIZATION FOR CATALYSIS IN THETITL 3 AMINOACYLASE-1/M20 FAMILY.REF J.BIOL.CHEM. V. 278 44496 2003REFN ISSN 0021-9258PMID 12933810DOI 10.1074/JBC.M304233200 Variant Set Distributions Mapped Variants
General Structure Information 1q7l ACY1 zn-binding domain of the t347g mutant of human aminoacylase- i 1.4Å AUTH H.A.LINDNER,V.V.LUNIN,A.ALARY,R.HECKER,M.CYGLER,AUTH 2 R.MENARDTITL ESSENTIAL ROLES OF ZINC LIGATION AND ENZYMETITL 2 DIMERIZATION FOR CATALYSIS IN THETITL 3 AMINOACYLASE-1/M20 FAMILY.REF J.BIOL.CHEM. V. 278 44496 2003REFN ISSN 0021-9258PMID 12933810DOI 10.1074/JBC.M304233200 Variant Set Distributions Mapped Variants
General Structure Information 1q7l ACY1 zn-binding domain of the t347g mutant of human aminoacylase- i 1.4Å AUTH H.A.LINDNER,V.V.LUNIN,A.ALARY,R.HECKER,M.CYGLER,AUTH 2 R.MENARDTITL ESSENTIAL ROLES OF ZINC LIGATION AND ENZYMETITL 2 DIMERIZATION FOR CATALYSIS IN THETITL 3 AMINOACYLASE-1/M20 FAMILY.REF J.BIOL.CHEM. V. 278 44496 2003REFN ISSN 0021-9258PMID 12933810DOI 10.1074/JBC.M304233200 Variant Set Distributions Mapped Variants
General Structure Information 2vze ACSM2A crystal structure of human acyl-coa synthetase medium-chain family member 2a (l64p mutation) in complex with amp 2.45Å AUTH G.KOCHAN,E.S.PILKA,F.V.DELFT,U.OPPERMANN,W.W.YUETITL STRUCTURAL SNAPSHOTS FOR THE CONFORMATION- DEPENDENTTITL 2 CATALYSIS BY HUMAN MEDIUM-CHAIN ACYL- COENZYME A SYNTHETASETITL 3 ACSM2A.REF J.MOL.BIOL. V. 388 997 2009REFN ISSN 0022-2836PMID 19345228DOI 10.1016/J.JMB.2009.03.064 Variant Set Distributions Ripley’s K […]
General Structure Information 3bxm FOLH1 structure of an inactive mutant of human glutamate carboxypeptidase ii [gcpii(e424a)] in complex with n-acetyl-asp-glu (naag) 1.71Å AUTH V.KLUSAK,C.BARINKA,A.PLECHANOVOVA,P.MLCOCHOVA,J.KONVALINKA,AUTH 2 L.RULISEK,J.LUBKOWSKITITL REACTION MECHANISM OF GLUTAMATE CARBOXYPEPTIDASE II REVEALEDTITL 2 BY MUTAGENESIS, X-RAY CRYSTALLOGRAPHY, AND COMPUTATIONALTITL 3 METHODS.REF BIOCHEMISTRY V. 48 4126 2009REFN ISSN 0006-2960PMID 19301871DOI 10.1021/BI900220S Variant Set Distributions Ripley’s […]
General Structure Information 1y8x UBE2M structural basis for recruitment of ubc12 by an e2-binding domain in nedd8s e1 2.4Å AUTH D.T.HUANG,A.PAYDAR,M.ZHUANG,M.B.WADDELL,J.M.HOLTON,AUTH 2 B.A.SCHULMANTITL STRUCTURAL BASIS FOR RECRUITMENT OF UBC12 BY AN E2TITL 2 BINDING DOMAIN IN NEDD8S E1.REF MOL.CELL V. 17 341 2005REFN ISSN 1097-2765PMID 15694336DOI 10.1016/J.MOLCEL.2004.12.020 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3l1z UBE2D3 crystal structure of the u-box domain of human e4b ubiquitin ligase in complex with ubch5c e2 ubiquitin conjugating enzyme 3.17Å AUTH R.C.BENIRSCHKE,J.R.THOMPSON,Y.NOMINE,E.WASIELEWSKI,AUTH 2 N.JURANIC,S.MACURA,S.HATAKEYAMA,K.I.NAKAYAMA,M.V.BOTUYAN,AUTH 3 G.MERTITL MOLECULAR BASIS FOR THE ASSOCIATION OF HUMAN E4B U BOXTITL 2 UBIQUITIN LIGASE WITH E2-CONJUGATING ENZYMES UBCH5C ANDTITL 3 UBC4.REF STRUCTURE V. 18 955 […]
General Structure Information 2awf UBE2G1 structure of human ubiquitin-conjugating enzyme e2 g1 2.1Å AUTH Y.SHENG,J.H.HONG,R.DOHERTY,T.SRIKUMAR,J.SHLOUSH,AUTH 2 G.V.AVVAKUMOV,J.R.WALKER,S.XUE,D.NECULAI,J.W.WAN,S.K.KIM,AUTH 3 C.H.ARROWSMITH,B.RAUGHT,S.DHE-PAGANONTITL A HUMAN UBIQUITIN CONJUGATING ENZYME (E2)-HECT E3 LIGASETITL 2 STRUCTURE-FUNCTION SCREEN.REF MOL CELL PROTEOMICS V. 11 329 2012REFNPMID 22496338DOI 10.1074/MCP.O111.013706 Variant Set Distributions Mapped Variants