Assessment of Structural Intolerance and Durability
General Structure Information 2kax S100A5 solution structure and dynamics of s100a5 in the apo and ca2+ -bound states -1.0Å AUTH I.BERTINI,S.DAS GUPTA,X.HU,T.KARAVELAS,C.LUCHINAT,AUTH 2 G.PARIGI,J.YUANTITL SOLUTION STRUCTURE AND DYNAMICS OF S100A5 IN THETITL 2 APO AND CA2+-BOUND STATESREF J.BIOL.INORG.CHEM. V. 14 1097 2009REFN ISSN 0949-8257PMID 19536568DOI 10.1007/S00775-009-0553-1 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2psr S100A7 human psoriasin (s100a7) ca2+ and zn2+ bound form (crystal form ii) 2.05Å AUTH D.E.BRODERSEN,J.NYBORG,M.KJELDGAARDTITL ZINC-BINDING SITE OF AN S100 PROTEIN REVEALED. TWO CRYSTALTITL 2 STRUCTURES OF CA2+-BOUND HUMAN PSORIASIN (S100A7) IN THETITL 3 ZN2+-LOADED AND ZN2+-FREE STATES.REF BIOCHEMISTRY V. 38 1695 1999REFN ISSN 0006-2960PMID 10026247DOI 10.1021/BI982483D Variant Set Distributions Ripley’s […]
General Structure Information 3zwh MYH9 ca2+-bound s100a4 c3s, c81s, c86s and f45w mutant complexed with myosin iia 1.94Å AUTH B.KISS,A.DUELLI,L.RADNAI,K.A.KEKESI,G.KATONA,L.NYITRAYTITL CRYSTAL STRUCTURE OF THE S100A4-NONMUSCLE MYOSIN IIA TAILTITL 2 FRAGMENT COMPLEX REVEALS AN ASYMMETRIC TARGET BINDINGTITL 3 MECHANISM.REF PROC.NATL.ACAD.SCI.USA V. 109 6048 2012REFN ISSN 0027-8424PMID 22460785DOI 10.1073/PNAS.1114732109 Variant Set Distributions Mapped Variants
General Structure Information 2luc S100A11 solution structure of human s100 calcium-binding protein a11 -1.0Å AUTH K.W.HUNG,Y.M.CHANG,C.YUTITL NMR STRUCTURE NOTE: THE STRUCTURE OF HUMAN CALCIUM-BOUNDTITL 2 S100A11.REF J.BIOMOL.NMR V. 54 211 2012REFN ISSN 0925-2738PMID 22903637DOI 10.1007/S10858-012-9661-2 Variant Set Distributions Mapped Variants
General Structure Information 4duq S100A2 the structure of ca2+-loaded s100a2 at 1.3a resolution 1.3Å AUTH M.KOCH,G.FRITZTITL THE STRUCTURE OF CA2+-LOADED S100A2 AT 1.3- ANGSTROMTITL 2 RESOLUTION.REF FEBS J. V. 279 1799 2012REFN ISSN 1742-464XPMID 22394450DOI 10.1111/J.1742-4658.2012.08556.X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1rk9 PVALB solution structure of human alpha-parvalbumin (minimized average structure) -1.0Å AUTH I.BAIG,I.BERTINI,C.DEL BIANCO,Y.K.GUPTA,Y.-M.LEE,AUTH 2 C.LUCHINAT,A.QUATTRONETITL PARAMAGNETISM-BASED REFINEMENT STRATEGY FOR THETITL 2 SOLUTION STRUCTURE OF HUMAN ALPHA-PARVALBUMINREF BIOCHEMISTRY V. 43 5562 2004REFN ISSN 0006-2960PMID 15122922DOI 10.1021/BI035879K Variant Set Distributions Mapped Variants
General Structure Information 4ggf S100A9 crystal structure of mn2+ bound calprotectin 1.6Å AUTH S.M.DAMO,T.E.KEHL-FIE,N.SUGITANI,M.E.HOLT,S.RATHI,AUTH 2 W.J.MURPHY,Y.ZHANG,C.BETZ,L.HENCH,G.FRITZ,E.P.SKAAR,AUTH 3 W.J.CHAZINTITL MOLECULAR BASIS FOR MANGANESE SEQUESTRATION BY CALPROTECTINTITL 2 AND ROLES IN THE INNATE IMMUNE RESPONSE TO INVADINGTITL 3 BACTERIAL PATHOGENS.REF PROC.NATL.ACAD.SCI.USA V. 110 3841 2013REFN ISSN 0027-8424PMID 23431180DOI 10.1073/PNAS.1220341110 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 1ttx OCM solution stucture of human beta parvalbumin (oncomodulin) refined with a paramagnetism based strategy -1.0Å AUTH E.BABINI,I.BERTINI,F.CAPOZZI,C.DEL BIANCO,AUTH 2 D.HOLLENDER,T.KISS,C.LUCHINAT,A.QUATTRONETITL SOLUTION STRUCTURE OF HUMAN BETA-PARVALBUMIN ANDTITL 2 STRUCTURAL COMPARISON WITH ITS PARALOGTITL 3 ALPHA-PARVALBUMIN AND WITH THEIR RAT ORTHOLOGS(,)REF BIOCHEMISTRY V. 43 16076 2004REFN ISSN 0006-2960PMID 15610002DOI 10.1021/BI048388O Variant Set Distributions […]
General Structure Information 2h61 S100B x-ray structure of human ca2+-loaded s100b 1.9Å AUTH T.OSTENDORP,E.LECLERC,A.GALICHET,M.KOCH,N.DEMLING,B.WEIGLE,AUTH 2 C.W.HEIZMANN,P.M.KRONECK,G.FRITZTITL STRUCTURAL AND FUNCTIONAL INSIGHTS INTO RAGE ACTIVATION BYTITL 2 MULTIMERIC S100B.REF EMBO J. V. 26 3868 2007REFN ISSN 0261-4189PMID 17660747DOI 10.1038/SJ.EMBOJ.7601805 Variant Set Distributions Mapped Variants
General Structure Information 4ggf S100A8 crystal structure of mn2+ bound calprotectin 1.6Å AUTH S.M.DAMO,T.E.KEHL-FIE,N.SUGITANI,M.E.HOLT,S.RATHI,AUTH 2 W.J.MURPHY,Y.ZHANG,C.BETZ,L.HENCH,G.FRITZ,E.P.SKAAR,AUTH 3 W.J.CHAZINTITL MOLECULAR BASIS FOR MANGANESE SEQUESTRATION BY CALPROTECTINTITL 2 AND ROLES IN THE INNATE IMMUNE RESPONSE TO INVADINGTITL 3 BACTERIAL PATHOGENS.REF PROC.NATL.ACAD.SCI.USA V. 110 3841 2013REFN ISSN 0027-8424PMID 23431180DOI 10.1073/PNAS.1220341110 Variant Set Distributions Mapped Variants