Assessment of Structural Intolerance and Durability
General Structure Information 3ox6 CABP1 crystal structure of the calcium sensor calcium-binding protein 1 (cabp1) 2.4Å AUTH F.FINDEISEN,D.L.MINORTITL STRUCTURAL BASIS FOR THE DIFFERENTIAL EFFECTS OF CABP1 ANDTITL 2 CALMODULIN ON CA(V)1.2 CALCIUM-DEPENDENT INACTIVATION.REF STRUCTURE V. 18 1617 2010REFN ISSN 0969-2126PMID 21134641DOI 10.1016/J.STR.2010.09.012 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2l5y STIM2 nmr structure of calcium-loaded stim2 ef-sam. -1.0Å AUTH L.ZHENG,P.B.STATHOPULOS,R.SCHINDL,G.Y.LI,C.ROMANIN,M.IKURATITL AUTO-INHIBITORY ROLE OF THE EF-SAM DOMAIN OF STIM PROTEINSTITL 2 IN STORE-OPERATED CALCIUM ENTRY.REF PROC.NATL.ACAD.SCI.USA V. 108 1337 2011REFN ISSN 0027-8424PMID 21217057DOI 10.1073/PNAS.1015125108 Variant Set Distributions Mapped Variants
General Structure Information 2i2r KCNIP1 crystal structure of the kchip1/kv4.3 t1 complex 3.35Å AUTH M.PIOLETTI,F.FINDEISEN,G.L.HURA,D.L.MINOR JR.TITL THREE-DIMENSIONAL STRUCTURE OF THE KCHIP1-KV4.3 T1 COMPLEXTITL 2 REVEALS A CROSS-SHAPED OCTAMERREF NAT.STRUCT.MOL.BIOL. V. 13 987 2006REFN ISSN 1545-9993PMID 17057713DOI 10.1038/NSMB1164 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4msp FKBP14 crystal structure of human peptidyl-prolyl cis-trans isomerase fkbp22 (aka fkbp14) containing two ef-hand motifs 1.9Å AUTH S.P.BOUDKO,Y.ISHIKAWA,J.NIX,M.S.CHAPMAN,H.P.BACHINGERTITL STRUCTURE OF HUMAN PEPTIDYL-PROLYL CIS-TRANS ISOMERASETITL 2 FKBP22 CONTAINING TWO EF-HAND MOTIFS.REF PROTEIN SCI. V. 23 67 2014REFN ISSN 0961-8368PMID 24272907DOI 10.1002/PRO.2391 Variant Set Distributions Mapped Variants
General Structure Information 2m0r S100A14 solution structure and dynamics of human s100a14 -1.0Å AUTH I.BERTINI,V.BORSI,L.CEROFOLINI,S.DAS GUPTA,M.FRAGAI,AUTH 2 C.LUCHINATTITL SOLUTION STRUCTURE AND DYNAMICS OF HUMAN S100A14.REF J.BIOL.INORG.CHEM. V. 18 183 2013REFN ISSN 0949-8257PMID 23197251DOI 10.1007/S00775-012-0963-3 Variant Set Distributions Mapped Variants
General Structure Information 2e30 CHP1 solution structure of the cytoplasmic region of na+/h+ exchanger 1 complexed with essential cofactor calcineurin b homologous protein 1 -1.0Å AUTH M.MISHIMA,S.WAKABAYASHI,C.KOJIMATITL SOLUTION STRUCTURE OF THE CYTOPLASMIC REGION OFTITL 2 NA+/H+ EXCHANGER 1 COMPLEXED WITH ESSENTIALTITL 3 COFACTOR CALCINEURIN B HOMOLOGOUS PROTEIN 1REF J.BIOL.CHEM. V. 282 2741 2007REFN ISSN 0021-9258PMID […]
General Structure Information 4nsc MICU1 crystal structure of cbara1 in the apo-form 3.2Å AUTH L.WANG,X.YANG,S.LI,Z.WANG,Y.LIU,J.FENG,Y.ZHU,Y.SHENTITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO MICU1 REGULATION OFTITL 2 MITOCHONDRIAL CALCIUM UPTAKE.REF EMBO J. V. 33 594 2014REFN ISSN 0261-4189PMID 24514027DOI 10.1002/EMBJ.201386523 Variant Set Distributions Mapped Variants
General Structure Information 1dgv CIB1 homology-based model of apo cib (calcium-and integrin- binding protein) -1.0Å AUTH P.M.HWANG,H.J.VOGELTITL STRUCTURES OF THE PLATELET CALCIUM- ANDTITL 2 INTEGRIN-BINDING PROTEIN AND THE ALPHAIIB-INTEGRINTITL 3 CYTOPLASMIC DOMAIN SUGGEST A MECHANISM FORTITL 4 CALCIUM-REGULATED RECOGNITION; HOMOLOGY MODELLINGTITL 5 AND NMR STUDIES.REF J.MOL.RECOG. V. 13 83 2000REFN ISSN 0952-3499PMID 10822252DOI 10.1002/(SICI)1099-1352(200003/04)13:23.3.CO;2-1 Variant […]
General Structure Information 2l51 S100A16 solution structure of calcium bound s100a16 -1.0Å AUTH E.BABINI,I.BERTINI,V.BORSI,V.CALDERONE,X.HU,C.LUCHINAT,AUTH 2 G.PARIGITITL STRUCTURAL CHARACTERIZATION OF HUMAN S100A16, A LOW-AFFINITYTITL 2 CALCIUM BINDER.REF J.BIOL.INORG.CHEM. V. 16 243 2011REFN ISSN 0949-8257PMID 21046186DOI 10.1007/S00775-010-0721-3 Variant Set Distributions Mapped Variants
General Structure Information 1iq3 REPS2 solution structure of the eps15 homology domain of a human pob1 -1.0Å AUTH S.KOSHIBA,T.KIGAWA,J.IWAHARA,A.KIKUCHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE EPS15 HOMOLOGY DOMAIN OFTITL 2 A HUMAN POB1 (PARTNER OF RALBP1).REF FEBS LETT. V. 442 138 1999REFN ISSN 0014-5793PMID 9928989DOI 10.1016/S0014-5793(98)01644-5 Variant Set Distributions Mapped Variants