General Structure Information
| PDB ID | 4ggf |
| HGNC Gene Label(s) | S100A9 |
| Structure Name | crystal structure of mn2+ bound calprotectin |
| Resolution | 1.6Å |
| Reference | AUTH S.M.DAMO,T.E.KEHL-FIE,N.SUGITANI,M.E.HOLT,S.RATHI,AUTH 2 W.J.MURPHY,Y.ZHANG,C.BETZ,L.HENCH,G.FRITZ,E.P.SKAAR,AUTH 3 W.J.CHAZINTITL MOLECULAR BASIS FOR MANGANESE SEQUESTRATION BY CALPROTECTINTITL 2 AND ROLES IN THE INNATE IMMUNE RESPONSE TO INVADINGTITL 3 BACTERIAL PATHOGENS.REF PROC.NATL.ACAD.SCI.USA V. 110 3841 2013REFN ISSN 0027-8424PMID 23431180DOI 10.1073/PNAS.1220341110 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 109 |
| Number Of SNVs | 23 |
| Number Of Permutations | 3113 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.225 |
| p-value | 0.075 |
COSMIC
| Number Of Residues | 109 |
| Number Of SNVs | 7 |
| Number Of Permutations | 2669 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.143 |
| p-value | 0.25 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 23 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | -0.047 |
| p-value | 0.903 |