Assessment of Structural Intolerance and Durability
General Structure Information 3ub2 TIRAP tir domain of mal/tirap 2.4Å AUTH Z.LIN,J.LU,W.ZHOU,Y.SHENTITL STRUCTURAL INSIGHTS INTO TIR DOMAIN SPECIFICITY OF THETITL 2 BRIDGING ADAPTOR MAL IN TLR4 SIGNALINGREF PLOS ONE V. 7 34202 2012REFN ESSN 1932-6203PMID 22485159DOI 10.1371/JOURNAL.PONE.0034202 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2l6a NLRP12 three-dimensional structure of the n-terminal effector pyrin domain of nlrp12 -1.0Å AUTH A.S.PINHEIRO,C.EIBL,Z.EKMAN-VURAL,R.SCHWARZENBACHER,W.PETITITL THE NLRP12 PYRIN DOMAIN: STRUCTURE, DYNAMICS, AND FUNCTIONALTITL 2 INSIGHTS.REF J.MOL.BIOL. V. 413 790 2011REFN ISSN 0022-2836PMID 21978668DOI 10.1016/J.JMB.2011.09.024 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ctj HDLBP solution structure of the 8th kh type i domain from human vigilin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 8TH KH TYPE I DOMAINTITL 2 FROM HUMAN VIGILINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2djv MARS solution structures of the whep-trs domain of human methionyl-trna synthetase -1.0Å AUTH M.SATO,A.SASAGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE WHEP-TRS DOMAIN OFTITL 2 HUMAN METHIONYL-TRNA SYNTHETASEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2of5 CRADD oligomeric death domain complex 3.2Å AUTH H.H.PARK,E.LOGETTE,S.RAUNSER,S.CUENIN,T.WALZ,J.TSCHOPP,H.WUTITL DEATH DOMAIN ASSEMBLY MECHANISM REVEALED BY CRYSTALTITL 2 STRUCTURE OF THE OLIGOMERIC PIDDOSOME CORE COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 128 533 2007REFN ISSN 0092-8674PMID 17289572DOI 10.1016/J.CELL.2007.01.019 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2cr4 SH3BP2 solution structure of the sh2 domain of human sh3bp2 protein -1.0Å AUTH R.HATTA,T.TOMIZAWA,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH2 DOMAIN OF HUMANTITL 2 SH3BP2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3crd CRADD nmr structure of the raidd card domain, 15 structures -1.0Å AUTH J.J.CHOU,H.MATSUO,H.DUAN,G.WAGNERTITL SOLUTION STRUCTURE OF THE RAIDD CARD AND MODEL FORTITL 2 CARD/CARD INTERACTION IN CASPASE-2 AND CASPASE-9TITL 3 RECRUITMENT.REF CELL(CAMBRIDGE,MASS.) V. 94 171 1998REFN ISSN 0092-8674PMID 9695946DOI 10.1016/S0092-8674(00)81417-8 Variant Set Distributions Mapped Variants
General Structure Information 2p3w HTRA3 crystal structure of the htra3 pdz domain bound to a phage-derived ligand (fgrwv) 1.7Å AUTH S.T.RUNYON,Y.ZHANG,B.A.APPLETON,S.L.SAZINSKY,P.WU,B.PAN,AUTH 2 C.WIESMANN,N.J.SKELTON,S.S.SIDHUTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE PDZ DOMAINS OFTITL 2 HUMAN HTRA1 AND HTRA3.REF PROTEIN SCI. V. 16 2454 2007REFN ISSN 0961-8368PMID 17962403DOI 10.1110/PS.073049407 Variant Set Distributions Mapped Variants
General Structure Information 3dpr VLDLR human rhinovirus 2 bound to a concatamer of the vldl receptor module v3 3.5Å AUTH J.QUEROL-AUDI,T.KONECSNI,J.POUS,O.CARUGO,I.FITA,N.VERDAGUER,AUTH 2 D.BLAASTITL MINOR GROUP HUMAN RHINOVIRUS-RECEPTOR INTERACTIONS: GEOMETRYTITL 2 OF MULTIMODULAR ATTACHMENT AND BASIS OF RECOGNITIONREF FEBS LETT. V. 583 235 2009REFN ISSN 0014-5793PMID 19073182DOI 10.1016/J.FEBSLET.2008.12.014 Variant Set Distributions Mapped Variants
General Structure Information 2yuw MYBPC1 solution structure of 2nd fibronectin domain of slow type myosin-binding protein c -1.0Å AUTH T.N.NIRAULA,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF 2ND FIBRONECTIN DOMAIN OFTITL 2 SLOW TYPE MYOSIN-BINDING PROTEIN CREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants