General Structure Information
| PDB ID | 2of5 |
| HGNC Gene Label(s) | CRADD |
| Structure Name | oligomeric death domain complex |
| Resolution | 3.2Å |
| Reference | AUTH H.H.PARK,E.LOGETTE,S.RAUNSER,S.CUENIN,T.WALZ,J.TSCHOPP,H.WUTITL DEATH DOMAIN ASSEMBLY MECHANISM REVEALED BY CRYSTALTITL 2 STRUCTURE OF THE OLIGOMERIC PIDDOSOME CORE COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 128 533 2007REFN ISSN 0092-8674PMID 17289572DOI 10.1016/J.CELL.2007.01.019 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 91 |
| Number Of SNVs | 25 |
| Number Of Permutations | 1736 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.027 |
| p-value | 0.942 |
COSMIC
| Number Of Residues | 91 |
| Number Of SNVs | 3 |
| Number Of Permutations | 109 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.333 |
| p-value | 0.968 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 25 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | -0.273 |
| p-value | 0.586 |