Assessment of Structural Intolerance and Durability
General Structure Information 1wgr GRB7 solution structure of the ra domain of human grb7 protein -1.0Å AUTH H.LI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RA DOMAIN OF HUMAN GRB7TITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1y8p PDK3 crystal structure of the pdk3-l2 complex 2.63Å AUTH M.KATO,J.L.CHUANG,S.C.TSO,R.M.WYNN,D.T.CHUANGTITL CRYSTAL STRUCTURE OF PYRUVATE DEHYDROGENASE KINASE 3 BOUNDTITL 2 TO LIPOYL DOMAIN 2 OF HUMAN PYRUVATE DEHYDROGENASE COMPLEX.REF EMBO J. V. 24 1763 2005REFN ISSN 0261-4189PMID 15861126DOI 10.1038/SJ.EMBOJ.7600663 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2miu FHL2 structure of fhl2 lim adaptor and its interaction with ski -1.0Å AUTH Y.YANG,Y.SUN,E.E.MEDRANO,X.TIAN,M.A.WEISSTITL STRUCTURE OF FHL2 LIM ADAPTOR AND ITS INTERACTION WITH SKIREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2k9u FLNC solution nmr structure of the filamin-migfilin complex -1.0Å AUTH S.S.ITHYCHANDA,M.DAS,Y.Q.MA,K.DING,X.WANG,S.GUPTA,C.WU,AUTH 2 E.F.PLOW,J.QINTITL MIGFILIN, A MOLECULAR SWITCH IN REGULATION OF INTEGRINTITL 2 ACTIVATION.REF J.BIOL.CHEM. V. 284 4713 2009REFN ISSN 0021-9258PMID 19074766DOI 10.1074/JBC.M807719200 Variant Set Distributions Mapped Variants
General Structure Information 3f31 SPTAN1 crystal structure of the n-terminal region of alphaii-spectrin tetramerization domain 2.3Å AUTH S.MEHBOOB,Y.SONG,M.WITEK,F.LONG,B.D.SANTARSIERO,AUTH 2 M.E.JOHNSON,L.W.FUNGTITL CRYSTAL STRUCTURE OF THE NONERYTHROID ALPHA-SPECTRINTITL 2 TETRAMERIZATION SITE REVEALS DIFFERENCES BETWEEN ERYTHROIDTITL 3 AND NONERYTHROID SPECTRIN TETRAMER FORMATION.REF J.BIOL.CHEM. V. 285 14572 2010REFN ISSN 0021-9258PMID 20228407DOI 10.1074/JBC.M109.080028 Variant Set Distributions Mapped Variants
General Structure Information 2k60 STIM1 nmr structure of calcium-loaded stim1 ef-sam -1.0Å AUTH P.B.STATHOPULOS,L.ZHENG,G.Y.LI,M.J.PLEVIN,M.IKURATITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO STIM1-MEDIATEDTITL 2 INITIATION OF STORE-OPERATED CALCIUM ENTRY.REF CELL(CAMBRIDGE,MASS.) V. 135 110 2008REFN ISSN 0092-8674PMID 18854159DOI 10.1016/J.CELL.2008.08.006 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2byg DLG2 2nd pdz domain of discs large homologue 2 1.85Å AUTH J.M.ELKINS,E.PAPAGRIGORIOU,G.BERRIDGE,X.YANG,C.PHILLIPS,AUTH 2 C.GILEADI,C.SAVITSKY,D.A.DOYLETITL STRUCTURE OF PICK1 AND OTHER PDZ DOMAINS OBTAINED WITH THETITL 2 HELP OF SELF-BINDING C-TERMINAL EXTENSIONS.REF PROTEIN SCI. V. 16 683 2007REFN ISSN 0961-8368PMID 17384233DOI 10.1110/PS.062657507 Variant Set Distributions Mapped Variants
General Structure Information 2cpn TARBP2 solution structure of the second dsrbd of tar rna-binding protein 2 -1.0Å AUTH T.NAGATA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND DSRBD OF TARTITL 2 RNA-BINDING PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4gxb SNX17 structure of the snx17 atypical ferm domain bound to the npxy motif of p-selectin 1.8Å AUTH R.GHAI,A.BUGARCIC,H.LIU,S.J.NORWOOD,S.SKELDAL,E.J.COULSON,AUTH 2 S.S.LI,R.D.TEASDALE,B.M.COLLINSTITL STRUCTURAL BASIS FOR ENDOSOMAL TRAFFICKING OF DIVERSETITL 2 TRANSMEMBRANE CARGOS BY PX-FERM PROTEINS.REF PROC.NATL.ACAD.SCI.USA V. 110 E643 2013REFN ISSN 0027-8424PMID 23382219DOI 10.1073/PNAS.1216229110 Variant Set Distributions Mapped Variants
General Structure Information 4bkx HDAC1 the structure of hdac1 in complex with the dimeric elm2-sant domain of mta1 from the nurd complex 3.0Å AUTH C.J.MILLARD,P.J.WATSON,I.CELARDO,Y.GORDIYENKO,S.M.COWLEY,AUTH 2 C.V.ROBINSON,L.FAIRALL,J.W.R.SCHWABETITL CLASS I HDACS SHARE A COMMON MECHANISM OF REGULATION BYTITL 2 INOSITOL PHOSPHATES.REF MOL.CELL V. 51 57 2013REFN ISSN 1097-2765PMID 23791785DOI 10.1016/J.MOLCEL.2013.05.020 Variant Set Distributions Ripley’s K Analysis […]