General Structure Information
| PDB ID | 2k60 |
| HGNC Gene Label(s) | STIM1 |
| Structure Name | nmr structure of calcium-loaded stim1 ef-sam |
| Resolution | -1.0Å |
| Reference | AUTH P.B.STATHOPULOS,L.ZHENG,G.Y.LI,M.J.PLEVIN,M.IKURATITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO STIM1-MEDIATEDTITL 2 INITIATION OF STORE-OPERATED CALCIUM ENTRY.REF CELL(CAMBRIDGE,MASS.) V. 135 110 2008REFN ISSN 0092-8674PMID 18854159DOI 10.1016/J.CELL.2008.08.006 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 144 |
| Number Of SNVs | 23 |
| Number Of Permutations | 2136 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.043 |
| p-value | 0.629 |
ClinVar
| Number Of Residues | 144 |
| Number Of SNVs | 5 |
| Number Of Permutations | 320 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.8 |
| p-value | 0.002 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 23 |
| Number Of ClinVar SNVs | 5 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.65 |
| p-value | 0.008 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
