Assessment of Structural Intolerance and Durability
General Structure Information 3dyt SNX9 crystal structure of snx9px-bar (230-595), c2221 2.08Å AUTH Q.WANG,H.Y.KAAN,R.N.HOODA,S.L.GOH,H.SONDERMANNTITL STRUCTURE AND PLASTICITY OF ENDOPHILIN AND SORTINGTITL 2 NEXIN 9.REF STRUCTURE V. 16 1574 2008REFN ISSN 0969-2126PMID 18940612DOI 10.1016/J.STR.2008.07.016 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3rpn GSTK1 crystal structure of human kappa class glutathione transferase in complex with s-hexylglutathione 1.9Å AUTH B.WANG,Y.PENG,T.ZHANG,J.DINGTITL CRYSTAL STRUCTURES AND KINETIC STUDIES OF HUMAN KAPPA CLASSTITL 2 GLUTATHIONE TRANSFERASE PROVIDE INSIGHTS INTO THE CATALYTICTITL 3 MECHANISM.REF BIOCHEM.J. V. 439 215 2011REFN ISSN 0264-6021PMID 21728995DOI 10.1042/BJ20110753 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3l4g FARSA crystal structure of homo sapiens cytoplasmic phenylalanyl-trna synthetase 3.3Å AUTH I.FINAROV,N.MOOR,N.KESSLER,L.KLIPCAN,M.G.SAFROTITL STRUCTURE OF HUMAN CYTOSOLIC PHENYLALANYL-TRNA SYNTHETASE:TITL 2 EVIDENCE FOR KINGDOM-SPECIFIC DESIGN OF THE ACTIVE SITESTITL 3 AND TRNA BINDING PATTERNS.REF STRUCTURE V. 18 343 2010REFN ISSN 0969-2126PMID 20223217DOI 10.1016/J.STR.2010.01.002 Variant Set Distributions Mapped Variants
General Structure Information 2zmf PDE10A crystal structure of the c-terminal gaf domain of human phosphodiesterase 10a 2.1Å AUTH N.HANDA,E.MIZOHATA,S.KISHISHITA,M.TOYAMA,S.MORITA,AUTH 2 T.UCHIKUBO-KAMO,R.AKASAKA,K.OMORI,J.KOTERA,T.TERADA,AUTH 3 M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF THE GAF-B DOMAIN FROM HUMANTITL 2 PHOSPHODIESTERASE 10A COMPLEXED WITH ITS LIGAND, CAMPREF J.BIOL.CHEM. V. 283 19657 2008REFN ISSN 0021-9258PMID 18477562DOI 10.1074/JBC.M800595200 Variant Set Distributions Mapped Variants
General Structure Information 2e5r DTNA solution structure of the zz domain of dystrobrevin alpha (dystrobrevin-alpha) -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZZ DOMAIN OFTITL 2 DYSTROBREVIN ALPHA (DYSTROBREVIN-ALPHA)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2crm FNDC3A solution structure of the forth fniii domain of human -1.0Å AUTH K.IZUMI,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FORTH FNIII DOMAIN OFTITL 2 HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yry PLEKHA6 solution structure of the ph domain of pleckstrin homology domain-containing family a member 6 from human -1.0Å AUTH H.LI,M.SATO,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OF PLECKSTRINTITL 2 HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 6 FROMTITL 3 HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ps4 MAST1 pdz domain from human microtubule-associated serine/threonine-protein kinase 1 1.85Å AUTH E.UGOCHUKWU,J.WANG,T.KROJER,J.R.C.MUNIZ,R.SETHI,A.C.W.PIKE,AUTH 2 A.ROOS,E.SALAH,R.COCKING,P.SAVITSKY,D.A.DOYLE,F.VON DELFT,AUTH 3 C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,A.EDWARDS,S.KNAPP,AUTH 4 J.M.ELKINS,STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL PDZ DOMAIN FROM HUMAN MICROTUBULE-ASSOCIATEDTITL 2 SERINE/THREONINE-PROTEIN KINASE 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4hhv COL4A3BP crystal structure of ceramide transfer protein pleckstrin homology domain 1.75Å AUTH J.PRASHEK,T.TRUONG,X.YAOTITL CRYSTAL STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM THETITL 2 CERAMIDE TRANSFER PROTEIN: IMPLICATIONS FOR CONFORMATIONALTITL 3 CHANGE UPON LIGAND BINDING.REF PLOS ONE V. 8 79590 2013REFN ESSN 1932-6203PMID 24260258DOI 10.1371/JOURNAL.PONE.0079590 Variant Set Distributions Mapped Variants
General Structure Information 2v9r ROBO1 first and second ig domains from human robo1 (form 2) 2.0Å AUTH C.MORLOT,N.M.THIELENS,R.B.RAVELLI,W.HEMRIKA,R.A.ROMIJN,AUTH 2 P.GROS,S.CUSACK,A.A.MCCARTHYTITL STRUCTURAL INSIGHTS INTO THE SLIT-ROBO COMPLEX.REF PROC.NAT.ACAD.SCI.USA V. 104 14923 2007REFN ISSN 0027-8424PMID 17848514DOI 10.1073/PNAS.0705310104 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants