Assessment of Structural Intolerance and Durability
General Structure Information 4nh3 DICER1 structure of human dicer platform-paz-connector helix cassette in complex with 13-mer sirna having 5-pu and uu-3 ends (2.6 angstrom resolution) 2.62Å AUTH Y.TIAN,D.K.SIMANSHU,J.B.MA,J.E.PARK,I.HEO,V.N.KIM,D.J.PATELTITL A PHOSPHATE-BINDING POCKET WITHIN THE PLATFORM-PAZ-CONNECTORTITL 2 HELIX CASSETTE OF HUMAN DICER.REF MOL.CELL V. 53 606 2014REFN ISSN 1097-2765PMID 24486018DOI 10.1016/J.MOLCEL.2014.01.003 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3nau ZHX2 crystal structure of zhx2 hd2 (zinc-fingers and homeoboxes protein 2, homeodomain 2) 2.7Å AUTH L.E.BIRD,J.REN,J.E.NETTLESHIP,G.E.FOLKERS,R.J.OWENS,AUTH 2 D.K.STAMMERSTITL NOVEL STRUCTURAL FEATURES IN TWO ZHX HOMEODOMAINS DERIVEDTITL 2 FROM A SYSTEMATIC STUDY OF SINGLE AND MULTIPLE DOMAINSREF BMC STRUCT.BIOL. V. 10 13 2010REFN ESSN 1472-6807PMID 20509910DOI 10.1186/1472-6807-10-13 Variant Set Distributions Mapped Variants
General Structure Information 2cu1 MAP3K2 solution structure of the pb1 domain of human protein kinase mekk2b -1.0Å AUTH K.INOUE,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PB1 DOMAIN OF HUMANTITL 2 PROTEIN KINASE MEKK2BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1x5x FNDC3A solution structure of the fibronectin type-iii domain of human fibronectin type iii domain containing protein 3 -1.0Å AUTH M.YONEYAMA,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIBRONECTIN TYPE-IIITITL 2 DOMAIN OF HUMAN FIBRONECTIN TYPE III DOMAINTITL 3 CONTAINING PROTEIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wk0 FNDC3A solution structure of fibronectin type iii domain derived from human kiaa0970 protein -1.0Å AUTH N.KOBAYASHI,S.KOSHIBA,M.INOUE,F.HAYASHI,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF FIBRONECTIN TYPE III DOMAINTITL 2 DERIVED FROM HUMAN KIAA0970 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4mvt PIAS3 crystal structure of sumo e3 ligase pias3 2.3Å AUTH J.HU,A.DONG,Y.LI,W.TEMPEL,C.BOUNTRA,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,Y.TONG,STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF SUMO E3 LIGASE PIAS3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2cxk CAMTA1 crystal structure of the tig domain of human calmodulin- binding transcription activator 1 (camta1) 1.85Å AUTH A.A.PIOSZAK,K.MURAYAMA,M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF THE TIG DOMAIN OF HUMANTITL 2 CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 1TITL 3 (CAMTA1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4ikd SNX11 crystal structure of snx11 px domain 1.6Å AUTH J.XU,T.XU,J.LIUTITL STRUCTURE OF SORTING NEXIN 11 (SNX11) REVEALS A NOVELTITL 2 EXTENDED PX DOMAIN (PXE DOMAIN) CRITICAL FOR THE INHIBITIONTITL 3 OF SORTING NEXIN 10 (SNX10) INDUCED VACUOLATIONREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2vwf GAB2 grb2 sh3c (2) 1.58Å AUTH M.HARKIOLAKI,T.TSIRKA,M.LEWITZKY,P.C.SIMISTER,AUTH 2 D.JOSHI,L.E.BIRD,E.Y.JONES,N.OREILLY,S.M.FELLERTITL DISTINCT BINDING MODES OF TWO EPITOPES IN GAB2TITL 2 THAT INTERACT WITH THE SH3C DOMAIN OF GRB2.REF STRUCTURE V. 17 809 2009REFN ISSN 0969-2126PMID 19523899DOI 10.1016/J.STR.2009.03.017 Variant Set Distributions Mapped Variants
General Structure Information 3bin EPB41L3 structure of the dal-1 and tslc1 (372-383) complex 2.3Å AUTH R.D.BUSAM,A.-G.THORSELL,A.FLORES,M.HAMMARSTROM,C.PERSSON,AUTH 2 B.OBRINK,B.M.HALLBERGTITL STRUCTURAL BASIS OF TUMOR SUPPRESSOR IN LUNG CANCER 1TITL 2 (TSLC1) BINDING TO DIFFERENTIALLY EXPRESSED INTITL 3 ADENOCARCINOMA OF THE LUNG (DAL-1/4.1B)REF J.BIOL.CHEM. V. 286 4511 2011REFN ISSN 0021-9258PMID 21131357DOI 10.1074/JBC.M110.174011 Variant Set Distributions Ripley’s K Analysis […]