Assessment of Structural Intolerance and Durability
General Structure Information 4cos ZMYND8 crystal structure of the phd-bromo-pwwp cassette of human prkcbp1 1.67Å AUTH P.FILIPPAKOPOULOSTITL CRYSTAL STRUCTURE OF THE PHD-BROMO-PWWP CASSETTE OF HUMANTITL 2 PRKCBP1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3zrh ZRANB1 crystal structure of the lys29, lys33-linkage-specific trabid otu deubiquitinase domain reveals an ankyrin-repeat ubiquitin binding domain (ankubd) 2.23Å AUTH J.D.F.LICCHESI,J.MIESZCZANEK,T.E.T.MEVISSEN,T.J.RUTHERFORD,AUTH 2 M.AKUTSU,S.VIRDEE,F.E.OUALID,J.W.CHIN,H.OVAA,M.BIENZ,AUTH 3 D.KOMANDERTITL AN ANKYRIN-REPEAT UBIQUITIN-BINDING DOMAIN DETERMINESTITL 2 TRABIDS SPECIFICITY FOR ATYPICAL UBIQUITIN CHAINS.REF NAT.STRUCT.MOL.BIOL. V. 19 62 2011REFN ISSN 1545-9993PMID 22157957DOI 10.1038/NSMB.2169 Variant Set Distributions Ripley’s K […]
General Structure Information 2dn6 SWAP70 solution structure of the ph domain of kiaa0640 protein from human -1.0Å AUTH H.LI,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OF KIAA0640TITL 2 PROTEIN FROM HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2da0 ASAP1 solution structure of the ph domain of pip2-dependent arf1 gtpase-activating protein from human -1.0Å AUTH H.LI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OFTITL 2 PIP2-DEPENDENT ARF1 GTPASE-ACTIVATING PROTEIN FROMTITL 3 HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1v5j IGSF9 solution structure of rsgi ruh-008, fn3 domain in human cdna -1.0Å AUTH Y.DOI-KATAYAMA,F.HAYASHI,H.HIROTA,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-008, A FN3 DOMAINTITL 2 IN HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3gf9 ITSN2 crystal structure of human intersectin 2 rhogef domain 2.5Å AUTH Y.SHEN,Y.TONG,W.TEMPEL,Y.LI,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN INTERSECTIN 2 RHOGEFTITL 2 DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2bye PLCE1 nmr solution structure of phospholipase c epsilon ra 1 domain -1.0Å AUTH T.D.BUNNEY,R.HARRIS,N.L.GANDARILLAS,M.B.JOSEPHS,AUTH 2 S.M.ROE,S.C.SORLI,H.F.PATERSON,F.RODRIGUES-LIMA,AUTH 3 D.ESPOSITO,C.P.PONTING,P.GIERSCHIK,L.H.PEARL,AUTH 4 P.C.DRISCOLL,M.KATANTITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO RASTITL 2 ASSOCIATION DOMAINS OF PHOSPHOLIPASE C EPSILON.REF MOL.CELL V. 21 495 2006REFN ISSN 1097-2765PMID 16483931DOI 10.1016/J.MOLCEL.2006.01.008 Variant Set Distributions Mapped Variants
General Structure Information 1ue9 ITSN2 solution structure of the fourth sh3 domain of human intersectin 2 (kiaa1256) -1.0Å AUTH N.TOCHIO,T.KIGAWA,S.KOSHIBA,N.KOBAYASHI,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FOURTH SH3 DOMAIN OFTITL 2 HUMAN INTERSECTIN 2 (KIAA1256)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dhz RAPGEFL1 solution structure of the ra domain in the human link guanine nucleotide exchange factor ii (link-gefii) -1.0Å AUTH C.ZHAO,T.KIGAWA,M.YONEYAMA,S.KOSHIBA,T.HARADA,AUTH 2 S.WATANABE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RA DOMAIN IN THE HUMANTITL 2 LINK GUANINE NUCLEOTIDE EXCHANGE FACTOR IITITL 3 (LINK-GEFII)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3h5c SERPINA10 x-ray structure of protein z-protein z inhibitor complex 3.26Å AUTH X.HUANG,A.DEMENTIEV,S.T.OLSON,P.G.GETTINSTITL BASIS FOR THE SPECIFICITY AND ACTIVATION OF THE SERPINTITL 2 PROTEIN Z-DEPENDENT PROTEINASE INHIBITOR (ZPI) AS ANTITL 3 INHIBITOR OF MEMBRANE-ASSOCIATED FACTOR XA.REF J.BIOL.CHEM. V. 285 20399 2010REFN ISSN 0021-9258PMID 20427285DOI 10.1074/JBC.M110.112748 Variant Set Distributions Ripley’s K Analysis Plots […]